HCSGD entry for CYP7B1
1. General information
| Official gene symbol | CYP7B1 |
|---|---|
| Entrez ID | 9420 |
| Gene full name | cytochrome P450, family 7, subfamily B, polypeptide 1 |
| Other gene symbols | CBAS3 CP7B SPG5A |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005506 | Iron ion binding | IEA | molecular_function |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0006699 | Bile acid biosynthetic process | IEA TAS | biological_process |
| GO:0006805 | Xenobiotic metabolic process | TAS | biological_process |
| GO:0008203 | Cholesterol metabolic process | IEA | biological_process |
| GO:0008206 | Bile acid metabolic process | TAS | biological_process |
| GO:0008219 | Cell death | IEA | biological_process |
| GO:0008396 | Oxysterol 7-alpha-hydroxylase activity | IEA | molecular_function |
| GO:0016125 | Sterol metabolic process | TAS | biological_process |
| GO:0020037 | Heme binding | IEA | molecular_function |
| GO:0033147 | Negative regulation of intracellular estrogen receptor signaling pathway | IEA | biological_process |
| GO:0033783 | 25-hydroxycholesterol 7alpha-hydroxylase activity | IEA | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0050679 | Positive regulation of epithelial cell proliferation | IEA | biological_process |
| GO:0060740 | Prostate gland epithelium morphogenesis | IEA | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2676080696 | 0.6097094487 | 0.9642316222 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2159519815 |
| GSE13712_SHEAR | Down | -0.3186028098 |
| GSE13712_STATIC | Down | -0.1361482273 |
| GSE19018 | Down | -0.0777977504 |
| GSE19899_A1 | Up | 0.1954371010 |
| GSE19899_A2 | Down | -0.0065733157 |
| PubMed_21979375_A1 | Up | 0.1335172034 |
| PubMed_21979375_A2 | Up | 0.0723859956 |
| GSE35957 | Down | -0.0532862888 |
| GSE36640 | Down | -0.0246614063 |
| GSE54402 | Up | 0.0585181802 |
| GSE9593 | Down | -0.1678225669 |
| GSE43922 | Up | 0.0225938055 |
| GSE24585 | Down | -0.0264077774 |
| GSE37065 | Up | 0.2288831786 |
| GSE28863_A1 | Up | 0.7365781187 |
| GSE28863_A2 | Up | 0.9554949466 |
| GSE28863_A3 | Up | 0.1034000382 |
| GSE28863_A4 | Down | -0.0264427473 |
| GSE48662 | Down | -0.0118470820 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018771 | Microarray | Functional MTI (Weak) | 18185580 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
