HCSGD entry for CD86

1. General information

Official gene symbolCD86
Entrez ID942
Gene full nameCD86 molecule
Other gene symbolsB7-2 B7.2 B70 CD28LG2 LAB72
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001878Response to yeastIEAbiological_process
GO:0002224Toll-like receptor signaling pathwayIEAbiological_process
GO:0002309T cell proliferation involved in immune responseIEAbiological_process
GO:0002668Negative regulation of T cell anergyIEAbiological_process
GO:0004872Receptor activityTASmolecular_function
GO:0005102Receptor bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0006955Immune responseTASbiological_process
GO:0007173Epidermal growth factor receptor signaling pathwayTASbiological_process
GO:0007267Cell-cell signalingICbiological_process
GO:0007568AgingIEAbiological_process
GO:0008284Positive regulation of cell proliferationTASbiological_process
GO:0008543Fibroblast growth factor receptor signaling pathwayTASbiological_process
GO:0009897External side of plasma membraneIEAcellular_component
GO:0015026Coreceptor activityNASmolecular_function
GO:0016021Integral component of membraneIC IEAcellular_component
GO:0016032Viral processIEAbiological_process
GO:0031295T cell costimulationTASbiological_process
GO:0034341Response to interferon-gammaIEAbiological_process
GO:0038095Fc-epsilon receptor signaling pathwayTASbiological_process
GO:0042104Positive regulation of activated T cell proliferationIEAbiological_process
GO:0042110T cell activationICbiological_process
GO:0042113B cell activationIEAbiological_process
GO:0042493Response to drugIEAbiological_process
GO:0043011Myeloid dendritic cell differentiationIEAbiological_process
GO:0043017Positive regulation of lymphotoxin A biosynthetic processNASbiological_process
GO:0043231Intracellular membrane-bounded organelleIEAcellular_component
GO:0045086Positive regulation of interleukin-2 biosynthetic processNASbiological_process
GO:0045087Innate immune responseTASbiological_process
GO:0045404Positive regulation of interleukin-4 biosynthetic processNASbiological_process
GO:0045630Positive regulation of T-helper 2 cell differentiationNASbiological_process
GO:0045893Positive regulation of transcription, DNA-templatedNASbiological_process
GO:0048011Neurotrophin TRK receptor signaling pathwayTASbiological_process
GO:0048015Phosphatidylinositol-mediated signalingTASbiological_process
GO:0051607Defense response to virusIEAbiological_process
GO:0071222Cellular response to lipopolysaccharideIEAbiological_process
GO:0071248Cellular response to metal ionIEAbiological_process
GO:0071345Cellular response to cytokine stimulusIEAbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.83589245090.44486756200.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0184970746
GSE13712_SHEARDown-0.1367748819
GSE13712_STATICDown-0.0820178820
GSE19018Up0.1302393062
GSE19899_A1Up0.0475236871
GSE19899_A2Up0.0831973625
PubMed_21979375_A1Up0.2246646050
PubMed_21979375_A2Down-0.1616715009
GSE35957Up0.1365460997
GSE36640Down-0.0309041492
GSE54402Up0.0773206891
GSE9593Down-0.0514173264
GSE43922Up0.0179117288
GSE24585Up0.2127324380
GSE37065Up0.0187765820
GSE28863_A1Down-0.3145991871
GSE28863_A2Down-0.3347440524
GSE28863_A3Up0.0946408760
GSE28863_A4Up0.0241208276
GSE48662Down-0.4100255407

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Anti-thymocyte Globulin (Rabbit)DB00098 BTD00040 | BIOD00040
AbataceptDB01281 -
BelataceptDB06681 -

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT022558MicroarrayFunctional MTI (Weak)18668037
Entries Per Page
Displaying Page of
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.