HCSGD entry for HTRA3
1. General information
| Official gene symbol | HTRA3 |
|---|---|
| Entrez ID | 94031 |
| Gene full name | HtrA serine peptidase 3 |
| Other gene symbols | Prsp Tasp |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001558 | Regulation of cell growth | IEA | biological_process |
| GO:0004175 | Endopeptidase activity | IDA | molecular_function |
| GO:0004252 | Serine-type endopeptidase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005520 | Insulin-like growth factor binding | IEA | molecular_function |
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0006508 | Proteolysis | IDA | biological_process |
| GO:0008236 | Serine-type peptidase activity | IDA | molecular_function |
| GO:0030512 | Negative regulation of transforming growth factor beta receptor signaling pathway | ISS | biological_process |
| GO:0030514 | Negative regulation of BMP signaling pathway | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2600930778 | 0.1285530603 | 0.9532038290 | 0.6902580783 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0580351638 |
| GSE13712_SHEAR | Down | -0.8288610722 |
| GSE13712_STATIC | Down | -0.2929006186 |
| GSE19018 | Up | 0.0879379965 |
| GSE19899_A1 | Down | -0.2399358054 |
| GSE19899_A2 | Down | -0.3747546389 |
| PubMed_21979375_A1 | Down | -0.3925286750 |
| PubMed_21979375_A2 | Down | -0.1082923007 |
| GSE35957 | Down | -0.3876568413 |
| GSE36640 | Down | -0.6929414827 |
| GSE54402 | Down | -0.0027248570 |
| GSE9593 | Down | -0.5591092604 |
| GSE43922 | Up | 0.0349116025 |
| GSE24585 | Down | -0.0416708418 |
| GSE37065 | Up | 0.4063075342 |
| GSE28863_A1 | Up | 1.0642530990 |
| GSE28863_A2 | Up | 0.8099859096 |
| GSE28863_A3 | Up | 0.3623783097 |
| GSE28863_A4 | Up | 0.1033891648 |
| GSE48662 | Up | 0.6583015843 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018144 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022741 | Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
