HCSGD entry for ATPIF1
1. General information
| Official gene symbol | ATPIF1 |
|---|---|
| Entrez ID | 93974 |
| Gene full name | ATPase inhibitory factor 1 |
| Other gene symbols | ATPI ATPIP IP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001525 | Angiogenesis | TAS | biological_process |
| GO:0001937 | Negative regulation of endothelial cell proliferation | IDA | biological_process |
| GO:0004857 | Enzyme inhibitor activity | TAS | molecular_function |
| GO:0005516 | Calmodulin binding | ISS | molecular_function |
| GO:0005739 | Mitochondrion | IDA ISS | cellular_component |
| GO:0005753 | Mitochondrial proton-transporting ATP synthase complex | IDA | cellular_component |
| GO:0006091 | Generation of precursor metabolites and energy | TAS | biological_process |
| GO:0006783 | Heme biosynthetic process | IMP | biological_process |
| GO:0009986 | Cell surface | IDA | cellular_component |
| GO:0030218 | Erythrocyte differentiation | IMP | biological_process |
| GO:0042030 | ATPase inhibitor activity | IDA ISS | molecular_function |
| GO:0042803 | Protein homodimerization activity | ISS | molecular_function |
| GO:0043532 | Angiostatin binding | IDA | molecular_function |
| GO:0045980 | Negative regulation of nucleotide metabolic process | IEA | biological_process |
| GO:0051117 | ATPase binding | IDA ISS | molecular_function |
| GO:0051260 | Protein homooligomerization | ISS | biological_process |
| GO:0051289 | Protein homotetramerization | ISS | biological_process |
| GO:0051346 | Negative regulation of hydrolase activity | IDA ISS | biological_process |
| GO:0072593 | Reactive oxygen species metabolic process | IEA | biological_process |
| GO:1901030 | Positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1800040880 | 0.7718332814 | 0.8315001053 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1664244212 |
| GSE13712_SHEAR | Up | 0.0467600354 |
| GSE13712_STATIC | Up | 0.2178904260 |
| GSE19018 | Up | 0.5182373731 |
| GSE19899_A1 | Up | 0.2989642431 |
| GSE19899_A2 | Up | 0.7766938741 |
| PubMed_21979375_A1 | Down | -0.0316517000 |
| PubMed_21979375_A2 | Up | 0.2349216292 |
| GSE35957 | Down | -0.0849144444 |
| GSE36640 | Down | -0.0020166150 |
| GSE54402 | Up | 0.1737479941 |
| GSE9593 | Down | -0.1287310679 |
| GSE43922 | Up | 0.0628382790 |
| GSE24585 | Up | 0.0416064716 |
| GSE37065 | Down | -0.0468924316 |
| GSE28863_A1 | Down | -0.5264803921 |
| GSE28863_A2 | Down | -0.1349481312 |
| GSE28863_A3 | Down | -0.1109529491 |
| GSE28863_A4 | Down | -0.0812883285 |
| GSE48662 | Up | 0.0448895172 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-615-3p | MIMAT0003283 | MIRT040414 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-3p | MIMAT0000762 | MIRT042994 | CLASH | Functional MTI (Weak) | 23622248 |
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