HCSGD entry for TGFBRAP1
1. General information
| Official gene symbol | TGFBRAP1 |
|---|---|
| Entrez ID | 9392 |
| Gene full name | transforming growth factor, beta receptor associated protein 1 |
| Other gene symbols | TRAP-1 TRAP1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005083 | Small GTPase regulator activity | IEA | molecular_function |
| GO:0005160 | Transforming growth factor beta receptor binding | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006355 | Regulation of transcription, DNA-templated | IDA | biological_process |
| GO:0006886 | Intracellular protein transport | IEA | biological_process |
| GO:0007165 | Signal transduction | IDA | biological_process |
| GO:0007179 | Transforming growth factor beta receptor signaling pathway | TAS | biological_process |
| GO:0016020 | Membrane | IDA | cellular_component |
| GO:0016192 | Vesicle-mediated transport | IEA | biological_process |
| GO:0046332 | SMAD binding | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0719410281 | 0.8394107253 | 0.5715393848 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1767893178 |
| GSE13712_SHEAR | Down | -0.0637538547 |
| GSE13712_STATIC | Down | -0.1573864048 |
| GSE19018 | Down | -0.0476815394 |
| GSE19899_A1 | Up | 0.0102939265 |
| GSE19899_A2 | Up | 0.6124015865 |
| PubMed_21979375_A1 | Up | 0.6959014822 |
| PubMed_21979375_A2 | Up | 1.0021455198 |
| GSE35957 | Up | 0.1531549188 |
| GSE36640 | Up | 0.1255919487 |
| GSE54402 | Up | 0.0277742233 |
| GSE9593 | Up | 0.3726684456 |
| GSE43922 | Up | 0.3289598879 |
| GSE24585 | Up | 0.0087174057 |
| GSE37065 | Up | 0.0296470483 |
| GSE28863_A1 | Down | -0.1744180113 |
| GSE28863_A2 | Up | 0.3266771676 |
| GSE28863_A3 | Down | -0.7013682214 |
| GSE28863_A4 | Down | -0.1448348649 |
| GSE48662 | Up | 0.6061967555 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-122-5p | MIMAT0000421 | MIRT023387 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-628-3p | MIMAT0003297 | MIRT039586 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049371 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
