HCSGD entry for NRXN2


1. General information

Official gene symbolNRXN2
Entrez ID9379
Gene full nameneurexin 2
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005246Calcium channel regulator activityISSmolecular_function
GO:0007155Cell adhesionIEAbiological_process
GO:0007268Synaptic transmissionIEA ISSbiological_process
GO:0007269Neurotransmitter secretionIEA ISSbiological_process
GO:0007416Synapse assemblyIEA ISSbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0046872Metal ion bindingIEAmolecular_function
GO:0050839Cell adhesion molecule bindingISSmolecular_function
GO:0051965Positive regulation of synapse assemblyIEAbiological_process
GO:0090129Positive regulation of synapse maturationIEAbiological_process
GO:0097104Postsynaptic membrane assemblyISSbiological_process
GO:0097109Neuroligin family protein bindingISSmolecular_function
GO:0097116Gephyrin clusteringISSbiological_process
GO:0097118Neuroligin clusteringISSbiological_process
GO:0097119Postsynaptic density protein 95 clusteringISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.33944168530.83760225680.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1006294158
GSE13712_SHEARDown-0.0274067809
GSE13712_STATICDown-0.1446950777
GSE19018Up0.2069077753
GSE19899_A1Down-0.0484228582
GSE19899_A2Up0.0093877958
PubMed_21979375_A1Down-0.2074627287
PubMed_21979375_A2Down-0.2763671831
GSE35957Down-0.0994665807
GSE36640Up0.0026716963
GSE54402Up0.0583217606
GSE9593Up0.2028869901
GSE43922Up0.0748385057
GSE24585Up0.2370988659
GSE37065Down-0.0260205942
GSE28863_A1Down-0.1035943937
GSE28863_A2Up0.1283353627
GSE28863_A3Up0.4664977598
GSE28863_A4Up0.0764121931
GSE48662Up0.2496292196

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.