HCSGD entry for SLC22A8
1. General information
| Official gene symbol | SLC22A8 |
|---|---|
| Entrez ID | 9376 |
| Gene full name | solute carrier family 22 (organic anion transporter), member 8 |
| Other gene symbols | OAT3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005080 | Protein kinase C binding | IEA | molecular_function |
| GO:0005452 | Inorganic anion exchanger activity | IDA | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0008514 | Organic anion transmembrane transporter activity | IEA | molecular_function |
| GO:0009636 | Response to toxic substance | IEA | biological_process |
| GO:0015075 | Ion transmembrane transporter activity | IEA | molecular_function |
| GO:0015651 | Quaternary ammonium group transmembrane transporter activity | IEA | molecular_function |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016323 | Basolateral plasma membrane | IDA | cellular_component |
| GO:0031427 | Response to methotrexate | IEA | biological_process |
| GO:0034635 | Glutathione transport | IEA | biological_process |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5128258843 | 0.8633500019 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0714199895 |
| GSE13712_SHEAR | Down | -0.0168893731 |
| GSE13712_STATIC | Down | -0.0802894964 |
| GSE19018 | Up | 0.0293794733 |
| GSE19899_A1 | Up | 0.0549611778 |
| GSE19899_A2 | Up | 0.0931506168 |
| PubMed_21979375_A1 | Down | -0.0588025681 |
| PubMed_21979375_A2 | Down | -0.0679378350 |
| GSE35957 | Up | 0.1491980080 |
| GSE36640 | Down | -0.0481532266 |
| GSE54402 | Up | 0.0023312897 |
| GSE9593 | Up | 0.2154543188 |
| GSE43922 | Up | 0.0359076429 |
| GSE24585 | Down | -0.0865862205 |
| GSE37065 | Down | -0.0478800010 |
| GSE28863_A1 | Down | -0.0145049835 |
| GSE28863_A2 | Up | 0.1829483445 |
| GSE28863_A3 | Up | 0.2602335102 |
| GSE28863_A4 | Up | 0.1045080699 |
| GSE48662 | Up | 0.3553320217 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Probenecid | DB01032 | APRD00167 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT028886 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
