HCSGD entry for KIF3B
1. General information
| Official gene symbol | KIF3B |
|---|---|
| Entrez ID | 9371 |
| Gene full name | kinesin family member 3B |
| Other gene symbols | FLA8 HH0048 KLP-11 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003777 | Microtubule motor activity | IEA TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005813 | Centrosome | NAS | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005871 | Kinesin complex | IEA | cellular_component |
| GO:0005873 | Plus-end kinesin complex | TAS | cellular_component |
| GO:0005876 | Spindle microtubule | NAS | cellular_component |
| GO:0007018 | Microtubule-based movement | IEA TAS | biological_process |
| GO:0007052 | Mitotic spindle organization | TAS | biological_process |
| GO:0007100 | Mitotic centrosome separation | TAS | biological_process |
| GO:0007368 | Determination of left/right symmetry | TAS | biological_process |
| GO:0007596 | Blood coagulation | TAS | biological_process |
| GO:0008017 | Microtubule binding | IEA | molecular_function |
| GO:0008089 | Anterograde axon cargo transport | TAS | biological_process |
| GO:0008152 | Metabolic process | TAS | biological_process |
| GO:0008574 | Plus-end-directed microtubule motor activity | TAS | molecular_function |
| GO:0016939 | Kinesin II complex | IDA | cellular_component |
| GO:0017048 | Rho GTPase binding | IPI | molecular_function |
| GO:0019886 | Antigen processing and presentation of exogenous peptide antigen via MHC class II | TAS | biological_process |
| GO:0030496 | Midbody | IEA | cellular_component |
| GO:0072383 | Plus-end-directed vesicle transport along microtubule | TAS | biological_process |
| GO:0090307 | Spindle assembly involved in mitosis | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0117418905 | 0.9225367197 | 0.2720583627 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.5045290708 |
| GSE13712_SHEAR | Down | -0.5106898841 |
| GSE13712_STATIC | Down | -0.1588585558 |
| GSE19018 | Up | 0.0773375886 |
| GSE19899_A1 | Up | 0.7735366059 |
| GSE19899_A2 | Up | 0.6327173039 |
| PubMed_21979375_A1 | Up | 0.3776894963 |
| PubMed_21979375_A2 | Up | 1.3268151118 |
| GSE35957 | Up | 0.5621045983 |
| GSE36640 | Up | 0.9229046963 |
| GSE54402 | Up | 1.0420169718 |
| GSE9593 | Up | 0.3844980152 |
| GSE43922 | Up | 0.3101131526 |
| GSE24585 | Down | -0.0229146959 |
| GSE37065 | Up | 0.0148871964 |
| GSE28863_A1 | Down | -0.1216629223 |
| GSE28863_A2 | Down | -0.2364887880 |
| GSE28863_A3 | Down | -0.5254339948 |
| GSE28863_A4 | Down | -0.0481657286 |
| GSE48662 | Up | 0.0951553394 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-324-5p | MIMAT0000761 | MIRT043232 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046602 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047522 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
