HCSGD entry for MYOCD

1. General information

Official gene symbolMYOCD
Entrez ID93649
Gene full namemyocardin
Other gene symbolsMYCD
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001046Core promoter sequence-specific DNA bindingIDAmolecular_function
GO:0001076RNA polymerase II transcription factor binding transcription factor activityISSmolecular_function
GO:0001077RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcriptionIDAmolecular_function
GO:0001666Response to hypoxiaIEPbiological_process
GO:0003257Positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiationIDAbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0006366Transcription from RNA polymerase II promoterIDA ISSbiological_process
GO:0008134Transcription factor bindingIPImolecular_function
GO:0008285Negative regulation of cell proliferationIDAbiological_process
GO:0019904Protein domain specific bindingIDAmolecular_function
GO:0035051Cardiocyte differentiationNASbiological_process
GO:0035065Regulation of histone acetylationISSbiological_process
GO:0045736Negative regulation of cyclin-dependent protein serine/threonine kinase activityIDAbiological_process
GO:0045893Positive regulation of transcription, DNA-templatedIDAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0045987Positive regulation of smooth muscle contractionIDAbiological_process
GO:0051091Positive regulation of sequence-specific DNA binding transcription factor activityIDAbiological_process
GO:0051145Smooth muscle cell differentiationIMPbiological_process
GO:0051150Regulation of smooth muscle cell differentiationTASbiological_process
GO:0051152Positive regulation of smooth muscle cell differentiationIDAbiological_process
GO:0055007Cardiac muscle cell differentiationISSbiological_process
GO:1900222Negative regulation of beta-amyloid clearanceIMPbiological_process
GO:2000721Positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiationIDAbiological_process
GO:2000724Positive regulation of cardiac vascular smooth muscle cell differentiationISSbiological_process
GO:2000727Positive regulation of cardiac muscle cell differentiationIDAbiological_process
GO:2001015Negative regulation of skeletal muscle cell differentiationIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.86583069030.00019993160.99999024730.0248226415

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-1.9897112023
GSE13712_SHEARUp0.0525836407
GSE13712_STATICDown-0.0998705686
GSE19018Up0.4852460355
GSE19899_A1Down-0.4537940054
GSE19899_A2Down-4.7854071853
PubMed_21979375_A1Down-1.7756891923
PubMed_21979375_A2Down-3.0020891116
GSE35957Down-0.8560425220
GSE36640Down-2.4584634948
GSE54402Down-0.9768663871
GSE9593Down-0.6943344824
GSE43922Down-1.3175052314
GSE24585Down-0.1463732259
GSE37065Up0.0575979991
GSE28863_A1Down-0.3883987429
GSE28863_A2Down-0.8948094493
GSE28863_A3Up1.0356997708
GSE28863_A4Down-0.1063505025
GSE48662Down-0.0172081747

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-1MIMAT0000416MIRT023927Western blotNon-Functional MTI20458751
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.