HCSGD entry for SLC22A6
1. General information
Official gene symbol | SLC22A6 |
---|---|
Entrez ID | 9356 |
Gene full name | solute carrier family 22 (organic anion transporter), member 6 |
Other gene symbols | HOAT1 OAT1 PAHT ROAT1 |
Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
---|---|---|---|
GO:0005452 | Inorganic anion exchanger activity | IDA | molecular_function |
GO:0005515 | Protein binding | IPI | molecular_function |
GO:0005886 | Plasma membrane | TAS | cellular_component |
GO:0005887 | Integral component of plasma membrane | IDA | cellular_component |
GO:0005901 | Caveola | IEA | cellular_component |
GO:0008514 | Organic anion transmembrane transporter activity | IDA IMP | molecular_function |
GO:0015347 | Sodium-independent organic anion transmembrane transporter activity | IDA IEA | molecular_function |
GO:0015711 | Organic anion transport | IDA IMP | biological_process |
GO:0015742 | Alpha-ketoglutarate transport | IDA | biological_process |
GO:0016323 | Basolateral plasma membrane | IDA | cellular_component |
GO:0031404 | Chloride ion binding | IEA | molecular_function |
GO:0031427 | Response to methotrexate | IEA | biological_process |
GO:0034220 | Ion transmembrane transport | IDA | biological_process |
GO:0042803 | Protein homodimerization activity | IEA | molecular_function |
GO:0043234 | Protein complex | IEA | cellular_component |
GO:0043252 | Sodium-independent organic anion transport | IDA IEA | biological_process |
GO:0051260 | Protein homooligomerization | IEA | biological_process |
GO:0055085 | Transmembrane transport | IDA TAS | biological_process |
GO:0097254 | Renal tubular secretion | IMP NAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
p-value up | p-value down | FDR up | FDR down |
---|---|---|---|
0.3829570457 | 0.9425454200 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
Data source | Up or down | Log fold change |
---|---|---|
GSE11954 | Down | -0.0400953280 |
GSE13712_SHEAR | Up | 0.1620443464 |
GSE13712_STATIC | Up | 0.0018990891 |
GSE19018 | Up | 0.0890120535 |
GSE19899_A1 | Up | 0.0533593116 |
GSE19899_A2 | Up | 0.1508569517 |
PubMed_21979375_A1 | Down | -0.0855598101 |
PubMed_21979375_A2 | Up | 0.0454687333 |
GSE35957 | Down | -0.0237555334 |
GSE36640 | Up | 0.0089405408 |
GSE54402 | Up | 0.0292290944 |
GSE9593 | Up | 0.0519625182 |
GSE43922 | Up | 0.0511330849 |
GSE24585 | Down | -0.0014974149 |
GSE37065 | Up | 0.0690283778 |
GSE28863_A1 | Up | 0.0042524652 |
GSE28863_A2 | Up | 0.0042816053 |
GSE28863_A3 | Up | 0.3572438958 |
GSE28863_A4 | Up | 0.1115654585 |
GSE48662 | Up | 0.4368170480 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
---|---|---|
Probenecid | DB01032 | APRD00167 |