HCSGD entry for SLC22A6


1. General information

Official gene symbolSLC22A6
Entrez ID9356
Gene full namesolute carrier family 22 (organic anion transporter), member 6
Other gene symbolsHOAT1 OAT1 PAHT ROAT1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005452Inorganic anion exchanger activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneIDAcellular_component
GO:0005901CaveolaIEAcellular_component
GO:0008514Organic anion transmembrane transporter activityIDA IMPmolecular_function
GO:0015347Sodium-independent organic anion transmembrane transporter activityIDA IEAmolecular_function
GO:0015711Organic anion transportIDA IMPbiological_process
GO:0015742Alpha-ketoglutarate transportIDAbiological_process
GO:0016323Basolateral plasma membraneIDAcellular_component
GO:0031404Chloride ion bindingIEAmolecular_function
GO:0031427Response to methotrexateIEAbiological_process
GO:0034220Ion transmembrane transportIDAbiological_process
GO:0042803Protein homodimerization activityIEAmolecular_function
GO:0043234Protein complexIEAcellular_component
GO:0043252Sodium-independent organic anion transportIDA IEAbiological_process
GO:0051260Protein homooligomerizationIEAbiological_process
GO:0055085Transmembrane transportIDA TASbiological_process
GO:0097254Renal tubular secretionIMP NASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.38295704570.94254542000.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0400953280
GSE13712_SHEARUp0.1620443464
GSE13712_STATICUp0.0018990891
GSE19018Up0.0890120535
GSE19899_A1Up0.0533593116
GSE19899_A2Up0.1508569517
PubMed_21979375_A1Down-0.0855598101
PubMed_21979375_A2Up0.0454687333
GSE35957Down-0.0237555334
GSE36640Up0.0089405408
GSE54402Up0.0292290944
GSE9593Up0.0519625182
GSE43922Up0.0511330849
GSE24585Down-0.0014974149
GSE37065Up0.0690283778
GSE28863_A1Up0.0042524652
GSE28863_A2Up0.0042816053
GSE28863_A3Up0.3572438958
GSE28863_A4Up0.1115654585
GSE48662Up0.4368170480

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

ProbenecidDB01032 APRD00167

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.