HCSGD entry for UBE4A
1. General information
| Official gene symbol | UBE4A |
|---|---|
| Entrez ID | 9354 |
| Gene full name | ubiquitination factor E4A |
| Other gene symbols | E4 UBOX2 UFD2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000151 | Ubiquitin ligase complex | IEA | cellular_component |
| GO:0000209 | Protein polyubiquitination | IEA | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006511 | Ubiquitin-dependent protein catabolic process | IEA | biological_process |
| GO:0034450 | Ubiquitin-ubiquitin ligase activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4168661601 | 0.4021853615 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3837403169 |
| GSE13712_SHEAR | Down | -0.3466122928 |
| GSE13712_STATIC | Up | 0.0521672255 |
| GSE19018 | Down | -0.3952149919 |
| GSE19899_A1 | Down | -0.0520152099 |
| GSE19899_A2 | Down | -0.3000464460 |
| PubMed_21979375_A1 | Down | -0.4269739675 |
| PubMed_21979375_A2 | Up | 0.0162715985 |
| GSE35957 | Down | -0.2058357917 |
| GSE36640 | Down | -0.0354792495 |
| GSE54402 | Up | 0.1081181255 |
| GSE9593 | Down | -0.2110969302 |
| GSE43922 | Up | 0.0051570877 |
| GSE24585 | Up | 0.2362161421 |
| GSE37065 | Down | -0.0134061309 |
| GSE28863_A1 | Up | 0.7261519748 |
| GSE28863_A2 | Up | 0.4557009096 |
| GSE28863_A3 | Down | -0.5114664197 |
| GSE28863_A4 | Up | 0.1455531646 |
| GSE48662 | Down | -0.0013798214 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT001399 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-17-5p | MIMAT0000070 | MIRT050796 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
