HCSGD entry for EFTUD2
1. General information
| Official gene symbol | EFTUD2 |
|---|---|
| Entrez ID | 9343 |
| Gene full name | elongation factor Tu GTP binding domain containing 2 |
| Other gene symbols | MFDGA MFDM Snrp116 Snu114 U5-116KD |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000398 | MRNA splicing, via spliceosome | IC TAS | biological_process |
| GO:0003924 | GTPase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA IEA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005681 | Spliceosomal complex | TAS | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006184 | GTP catabolic process | TAS | biological_process |
| GO:0006397 | MRNA processing | TAS | biological_process |
| GO:0008380 | RNA splicing | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0015030 | Cajal body | IDA | cellular_component |
| GO:0016607 | Nuclear speck | IDA | cellular_component |
| GO:0071013 | Catalytic step 2 spliceosome | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4886274040 | 0.6830202082 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0698932799 |
| GSE13712_SHEAR | Down | -0.0067794104 |
| GSE13712_STATIC | Down | -0.0308859172 |
| GSE19018 | Down | -0.0936669477 |
| GSE19899_A1 | Down | -0.0871180940 |
| GSE19899_A2 | Up | 0.1912685921 |
| PubMed_21979375_A1 | Up | 0.9525066981 |
| PubMed_21979375_A2 | Up | 0.6616401720 |
| GSE35957 | Down | -0.2206541832 |
| GSE36640 | Down | -0.2779228980 |
| GSE54402 | Up | 0.1476615939 |
| GSE9593 | Down | -0.3129492073 |
| GSE43922 | Up | 0.2372212545 |
| GSE24585 | Up | 0.1082675703 |
| GSE37065 | Down | -0.0468461138 |
| GSE28863_A1 | Up | 0.0088204577 |
| GSE28863_A2 | Up | 0.0970704829 |
| GSE28863_A3 | Down | -0.1545460415 |
| GSE28863_A4 | Down | -0.0050261685 |
| GSE48662 | Down | -0.3454318534 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-375 | MIMAT0000728 | MIRT019894 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-1 | MIMAT0000416 | MIRT023995 | Proteomics;Microarray | Non-Functional MTI (Weak) | 18668037 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041595 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-363-3p | MIMAT0000707 | MIRT044048 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049755 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
