HCSGD entry for VAMP3
1. General information
| Official gene symbol | VAMP3 |
|---|---|
| Entrez ID | 9341 |
| Gene full name | vesicle-associated membrane protein 3 |
| Other gene symbols | CEB |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000149 | SNARE binding | IBA | molecular_function |
| GO:0001921 | Positive regulation of receptor recycling | IEA ISS | biological_process |
| GO:0005484 | SNAP receptor activity | IBA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005886 | Plasma membrane | ISS | cellular_component |
| GO:0006461 | Protein complex assembly | IEA | biological_process |
| GO:0006887 | Exocytosis | TAS | biological_process |
| GO:0006904 | Vesicle docking involved in exocytosis | TAS | biological_process |
| GO:0006906 | Vesicle fusion | IBA | biological_process |
| GO:0007269 | Neurotransmitter secretion | IBA | biological_process |
| GO:0008021 | Synaptic vesicle | IBA | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016192 | Vesicle-mediated transport | ISS | biological_process |
| GO:0016324 | Apical plasma membrane | IEA | cellular_component |
| GO:0017075 | Syntaxin-1 binding | IEA | molecular_function |
| GO:0017156 | Calcium ion-dependent exocytosis | IEA | biological_process |
| GO:0030054 | Cell junction | IEA | cellular_component |
| GO:0030136 | Clathrin-coated vesicle | IDA | cellular_component |
| GO:0030141 | Secretory granule | IEA | cellular_component |
| GO:0030665 | Clathrin-coated vesicle membrane | IEA | cellular_component |
| GO:0031201 | SNARE complex | IBA IEA | cellular_component |
| GO:0034446 | Substrate adhesion-dependent cell spreading | IEA ISS | biological_process |
| GO:0042147 | Retrograde transport, endosome to Golgi | IDA | biological_process |
| GO:0043001 | Golgi to plasma membrane protein transport | IEA | biological_process |
| GO:0043005 | Neuron projection | IEA | cellular_component |
| GO:0055037 | Recycling endosome | IDA IEA | cellular_component |
| GO:0061025 | Membrane fusion | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4571474298 | 0.1700255917 | 0.9999902473 | 0.7976545714 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3528812968 |
| GSE13712_SHEAR | Down | -0.1159156457 |
| GSE13712_STATIC | Down | -0.1664203974 |
| GSE19018 | Up | 0.0757936100 |
| GSE19899_A1 | Down | -0.5350679559 |
| GSE19899_A2 | Down | -0.1507426611 |
| PubMed_21979375_A1 | Down | -0.2802837681 |
| PubMed_21979375_A2 | Down | -0.2196865952 |
| GSE35957 | Up | 0.3098681383 |
| GSE36640 | Up | 0.7152767911 |
| GSE54402 | Up | 0.0606546920 |
| GSE9593 | Up | 0.7476087696 |
| GSE43922 | Down | -0.1298172685 |
| GSE24585 | Up | 0.2175866697 |
| GSE37065 | Up | 0.0321721572 |
| GSE28863_A1 | Down | -0.3314319042 |
| GSE28863_A2 | Up | 0.0664928003 |
| GSE28863_A3 | Down | -0.8632002111 |
| GSE28863_A4 | Down | -0.2015207596 |
| GSE48662 | Up | 0.0707146504 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT001487 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT002594 | Microarray//qRT-PCR | Functional MTI (Weak) | 16549876 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT002594 | Microarray | Functional MTI (Weak) | 15685193 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT002594 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027733 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028609 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031281 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032396 | Proteomics | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 25412306 | We identified 107 proteins that could be potential markers of senescence and validated 10 of them (DEP1, NTAL, EBP50, STX4, VAMP3, ARMX3, B2MG, LANCL1, VPS26A and PLD3) |
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