HCSGD entry for GTF3C5
1. General information
| Official gene symbol | GTF3C5 |
|---|---|
| Entrez ID | 9328 |
| Gene full name | general transcription factor IIIC, polypeptide 5, 63kDa |
| Other gene symbols | TFIIIC63 TFIIICepsilon TFiiiC2-63 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000127 | Transcription factor TFIIIC complex | IDA | cellular_component |
| GO:0003677 | DNA binding | IC | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IC | biological_process |
| GO:0006383 | Transcription from RNA polymerase III promoter | IC TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0035914 | Skeletal muscle cell differentiation | IEA | biological_process |
| GO:0042791 | 5S class rRNA transcription from RNA polymerase III type 1 promoter | IC | biological_process |
| GO:0042797 | TRNA transcription from RNA polymerase III promoter | IC | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7348141902 | 0.3131578701 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0764653506 |
| GSE13712_SHEAR | Down | -0.0590184961 |
| GSE13712_STATIC | Up | 0.0355054036 |
| GSE19018 | Up | 0.0015836193 |
| GSE19899_A1 | Down | -0.0842421436 |
| GSE19899_A2 | Down | -0.2373127627 |
| PubMed_21979375_A1 | Up | 0.4026687873 |
| PubMed_21979375_A2 | Up | 0.3266046278 |
| GSE35957 | Down | -0.4549591545 |
| GSE36640 | Down | -0.4159139386 |
| GSE54402 | Down | -0.2178487346 |
| GSE9593 | Down | -0.4607902915 |
| GSE43922 | Up | 0.0544401879 |
| GSE24585 | Up | 0.0736864543 |
| GSE37065 | Down | -0.0694463115 |
| GSE28863_A1 | Down | -0.0153607619 |
| GSE28863_A2 | Down | -0.1695316690 |
| GSE28863_A3 | Down | -0.3733980625 |
| GSE28863_A4 | Up | 0.1220016073 |
| GSE48662 | Up | 0.5844099440 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT023140 | Proteomics;Microarray | Non-Functional MTI (Weak) | 18668037 |
| hsa-miR-7-5p | MIMAT0000252 | MIRT025954 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT037096 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-652-3p | MIMAT0003322 | MIRT039525 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046697 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052437 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
