HCSGD entry for MMP20


1. General information

Official gene symbolMMP20
Entrez ID9313
Gene full namematrix metallopeptidase 20
Other gene symbolsAI2A2 MMP-20
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004222Metalloendopeptidase activityIEAmolecular_function
GO:0005509Calcium ion bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005576Extracellular regionTAScellular_component
GO:0005578Proteinaceous extracellular matrixIEAcellular_component
GO:0005615Extracellular spaceTAScellular_component
GO:0006508ProteolysisIEAbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0022617Extracellular matrix disassemblyTASbiological_process
GO:0030198Extracellular matrix organizationTASbiological_process
GO:0030574Collagen catabolic processTASbiological_process
GO:0070173Regulation of enamel mineralizationTASbiological_process
GO:0097186AmelogenesisIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.82887522890.73500966910.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0714962521
GSE13712_SHEARDown-0.0092380562
GSE13712_STATICDown-0.0077111222
GSE19018Down-0.0871820095
GSE19899_A1Up0.0097147305
GSE19899_A2Up0.0265007248
PubMed_21979375_A1Down-0.1009241067
PubMed_21979375_A2Down-0.1667571416
GSE35957Up0.0102022506
GSE36640Down-0.0257114973
GSE54402Up0.1153576914
GSE9593Up0.0174790045
GSE43922Up0.0162634370
GSE24585Up0.0241793967
GSE37065Down-0.0275233946
GSE28863_A1Up0.0407550010
GSE28863_A2Down-0.0874368826
GSE28863_A3Up0.0890399637
GSE28863_A4Up0.1021597653
GSE48662Up0.0174721095

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

MarimastatDB00786 APRD00559
N-ISOBUTYL-N-[4-METHOXYPHENYLSULFONYL]GLYCYL HYDROXAMIC ACIDDB08271 -

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT016744MicroarrayFunctional MTI (Weak)18185580
hsa-miR-215-5pMIMAT0000272MIRT024491MicroarrayFunctional MTI (Weak)19074876
hsa-miR-192-5pMIMAT0000222MIRT026110MicroarrayFunctional MTI (Weak)19074876
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.