HCSGD entry for NAPRT1
1. General information
| Official gene symbol | NAPRT1 |
|---|---|
| Entrez ID | 93100 |
| Gene full name | nicotinate phosphoribosyltransferase domain containing 1 |
| Other gene symbols | PP3856 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004514 | Nicotinate-nucleotide diphosphorylase (carboxylating) activity | IEA | molecular_function |
| GO:0004516 | Nicotinate phosphoribosyltransferase activity | IDA IEA TAS | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0005829 | Cytosol | IDA TAS | cellular_component |
| GO:0006766 | Vitamin metabolic process | TAS | biological_process |
| GO:0006767 | Water-soluble vitamin metabolic process | TAS | biological_process |
| GO:0006769 | Nicotinamide metabolic process | TAS | biological_process |
| GO:0006979 | Response to oxidative stress | IMP | biological_process |
| GO:0009435 | NAD biosynthetic process | IEA | biological_process |
| GO:0016874 | Ligase activity | IEA | molecular_function |
| GO:0019358 | Nicotinate nucleotide salvage | IEA | biological_process |
| GO:0019674 | NAD metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9173798184 | 0.1104330231 | 0.9999902473 | 0.6362678118 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0639082115 |
| GSE13712_SHEAR | Down | -0.4753752115 |
| GSE13712_STATIC | Down | -0.0844682464 |
| GSE19018 | Up | 0.1161052144 |
| GSE19899_A1 | Down | -0.1609485758 |
| GSE19899_A2 | Down | -0.6231208327 |
| PubMed_21979375_A1 | Up | 0.0727716626 |
| PubMed_21979375_A2 | Down | -0.3527575269 |
| GSE35957 | Down | -0.0372941615 |
| GSE36640 | Down | -0.2575792087 |
| GSE54402 | Up | 0.0081207212 |
| GSE9593 | Down | -0.3670947110 |
| GSE43922 | Down | -0.3732802096 |
| GSE24585 | Up | 0.3212549491 |
| GSE37065 | Down | -0.0871022900 |
| GSE28863_A1 | Down | -0.1694206754 |
| GSE28863_A2 | Down | -0.0578352659 |
| GSE28863_A3 | Up | 0.3914420851 |
| GSE28863_A4 | Up | 0.0407648317 |
| GSE48662 | Down | -0.0681119939 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049798 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
