HCSGD entry for CD19

1. General information

Official gene symbolCD19
Entrez ID930
Gene full nameCD19 molecule
Other gene symbolsB4 CVID3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005057Receptor signaling protein activityTASmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006968Cellular defense responseTASbiological_process
GO:0007166Cell surface receptor signaling pathwayTASbiological_process
GO:0007173Epidermal growth factor receptor signaling pathwayTASbiological_process
GO:0008543Fibroblast growth factor receptor signaling pathwayTASbiological_process
GO:0009897External side of plasma membraneIDAcellular_component
GO:0038095Fc-epsilon receptor signaling pathwayTASbiological_process
GO:0045087Innate immune responseTASbiological_process
GO:0048011Neurotrophin TRK receptor signaling pathwayTASbiological_process
GO:0048015Phosphatidylinositol-mediated signalingTASbiological_process
GO:0050776Regulation of immune responseTASbiological_process
GO:0050853B cell receptor signaling pathwayIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.69779343110.54944960300.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0511917351
GSE13712_SHEARUp0.0912441118
GSE13712_STATICDown-0.1029203321
GSE19018Up0.1045220411
GSE19899_A1Down-0.0068064070
GSE19899_A2Up0.1191243292
PubMed_21979375_A1Down-0.0100772830
PubMed_21979375_A2Up0.0907334106
GSE35957Up0.3124454415
GSE36640Down-0.0964770202
GSE54402Down-0.0072750690
GSE9593Down-0.0542022348
GSE43922Up0.0591751270
GSE24585Down-0.0082098743
GSE37065Down-0.0660714343
GSE28863_A1Down-0.3604440988
GSE28863_A2Down-0.3566562099
GSE28863_A3Up0.3306294620
GSE28863_A4Up0.0389200370
GSE48662Down-0.0341527384

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

BlinatumomabDB09052 -

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 2 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

26196672All cells were negative for leukocyte markers (CD19, CD34, CD45) and CD73 positive
241703702%, respectively; all cells were negative for CD11b, CD19, and CD45
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