HCSGD entry for SRSF11
1. General information
| Official gene symbol | SRSF11 |
|---|---|
| Entrez ID | 9295 |
| Gene full name | serine/arginine-rich splicing factor 11 |
| Other gene symbols | NET2 SFRS11 dJ677H15.2 p54 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000166 | Nucleotide binding | IEA | molecular_function |
| GO:0000398 | MRNA splicing, via spliceosome | TAS | biological_process |
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0006366 | Transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0006369 | Termination of RNA polymerase II transcription | TAS | biological_process |
| GO:0006397 | MRNA processing | TAS | biological_process |
| GO:0006406 | MRNA export from nucleus | TAS | biological_process |
| GO:0008380 | RNA splicing | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0031124 | MRNA 3'-end processing | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5413158695 | 0.2459888682 | 0.9999902473 | 0.9545441545 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1742749211 |
| GSE13712_SHEAR | Up | 0.0635997586 |
| GSE13712_STATIC | Down | -0.0126953357 |
| GSE19018 | Up | 0.4124352000 |
| GSE19899_A1 | Down | -0.1294127357 |
| GSE19899_A2 | Down | -0.1008798252 |
| PubMed_21979375_A1 | Down | -0.7706781302 |
| PubMed_21979375_A2 | Down | -0.3236376517 |
| GSE35957 | Up | 0.1721538012 |
| GSE36640 | Up | 0.3147352566 |
| GSE54402 | Down | -0.4459636026 |
| GSE9593 | Down | -0.4241835478 |
| GSE43922 | Down | -0.0718333202 |
| GSE24585 | Up | 0.0429366940 |
| GSE37065 | Up | 0.1739358884 |
| GSE28863_A1 | Up | 0.1483478983 |
| GSE28863_A2 | Up | 0.5270723225 |
| GSE28863_A3 | Down | -0.0955148626 |
| GSE28863_A4 | Down | -0.2688085530 |
| GSE48662 | Down | -0.0359872450 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-376a-5p | MIMAT0003386 | MIRT004025 | Luciferase reporter assay | Functional MTI | 17322061 |
| hsa-miR-376a-3p | MIMAT0000729 | MIRT019666 | Reporter assay | Functional MTI | 17322061 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030735 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-423-5p | MIMAT0004748 | MIRT038024 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT045297 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-376a-5p | MIMAT0003386 | 1 | hsa-miR-376a* | 17322061 | |||
| hsa-miR-376a-5p | MIMAT0003386 | 2 | hsa-miR-376a* | 17322061 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
