HCSGD entry for MGME1
1. General information
| Official gene symbol | MGME1 |
|---|---|
| Entrez ID | 92667 |
| Gene full name | mitochondrial genome maintenance exonuclease 1 |
| Other gene symbols | C20orf72 DDK1 MTDPS11 bA504H3.4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000002 | Mitochondrial genome maintenance | IMP | biological_process |
| GO:0000738 | DNA catabolic process, exonucleolytic | IDA | biological_process |
| GO:0005739 | Mitochondrion | IDA IEA | cellular_component |
| GO:0006308 | DNA catabolic process | IDA | biological_process |
| GO:0008297 | Single-stranded DNA exodeoxyribonuclease activity | IDA IEA | molecular_function |
| GO:0043504 | Mitochondrial DNA repair | IEA IMP | biological_process |
| GO:0090305 | Nucleic acid phosphodiester bond hydrolysis | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0577823867 | 0.3297425402 | 0.5209094798 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.6838844488 |
| GSE13712_SHEAR | Up | 0.0714001531 |
| GSE13712_STATIC | Down | -0.0718887262 |
| GSE19018 | Up | 0.4548566361 |
| GSE19899_A1 | Up | 0.8848911924 |
| GSE19899_A2 | Down | -0.0966449377 |
| PubMed_21979375_A1 | Up | 0.2928151012 |
| PubMed_21979375_A2 | Up | 0.1331600618 |
| GSE35957 | Down | -1.1382092519 |
| GSE36640 | Down | -0.7474144989 |
| GSE54402 | Down | -0.0587546094 |
| GSE9593 | Down | -0.0405044158 |
| GSE43922 | Up | 0.0954082156 |
| GSE24585 | Up | 0.4206130196 |
| GSE37065 | Up | 0.0315074464 |
| GSE28863_A1 | Down | -0.1778380497 |
| GSE28863_A2 | Up | 0.2725841791 |
| GSE28863_A3 | Down | -0.4736423574 |
| GSE28863_A4 | Up | 0.3869501838 |
| GSE48662 | Down | -0.4993487464 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-let-7b-5p | MIMAT0000063 | MIRT005230 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
