HCSGD entry for CYTH2
1. General information
| Official gene symbol | CYTH2 |
|---|---|
| Entrez ID | 9266 |
| Gene full name | cytohesin 2 |
| Other gene symbols | ARNO CTS18 CTS18.1 PSCD2 PSCD2L SEC7L Sec7p-L Sec7p-like |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005086 | ARF guanyl-nucleotide exchange factor activity | IBA IEA ISS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005802 | Trans-Golgi network | IBA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0006897 | Endocytosis | TAS | biological_process |
| GO:0008289 | Lipid binding | IEA | molecular_function |
| GO:0016020 | Membrane | TAS | cellular_component |
| GO:0016192 | Vesicle-mediated transport | IBA | biological_process |
| GO:0030036 | Actin cytoskeleton organization | TAS | biological_process |
| GO:0030155 | Regulation of cell adhesion | IBA | biological_process |
| GO:0032012 | Regulation of ARF protein signal transduction | IEA | biological_process |
| GO:0043087 | Regulation of GTPase activity | IBA ISS TAS | biological_process |
| GO:0070679 | Inositol 1,4,5 trisphosphate binding | ISS | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1156368451 | 0.9371592113 | 0.6984365451 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2736297918 |
| GSE13712_SHEAR | Up | 0.1142627681 |
| GSE13712_STATIC | Down | -0.1513125804 |
| GSE19018 | Down | -0.4043349580 |
| GSE19899_A1 | Down | -0.0023307114 |
| GSE19899_A2 | Up | 0.0597710205 |
| PubMed_21979375_A1 | Down | -0.0449592117 |
| PubMed_21979375_A2 | Up | 0.1224831232 |
| GSE35957 | Down | -0.0836101526 |
| GSE36640 | Up | 0.3699841678 |
| GSE54402 | Up | 0.4016932983 |
| GSE9593 | Down | -0.0185184950 |
| GSE43922 | Up | 0.0098004345 |
| GSE24585 | Up | 0.2656082854 |
| GSE37065 | Down | -0.0913784790 |
| GSE28863_A1 | Up | 0.2273297265 |
| GSE28863_A2 | Up | 0.1256093339 |
| GSE28863_A3 | Up | 0.4510638981 |
| GSE28863_A4 | Up | 0.1473411668 |
| GSE48662 | Up | 0.3387503072 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Inositol 1,3,4,5-Tetrakisphosphate | DB01863 | EXPT01943 | DB03265 |
| Formic Acid | DB01942 | EXPT01461 |
| D-Myo-Inositol-1,4,5-Triphosphate | DB03401 | EXPT01811 |
| S,S-(2-Hydroxyethyl)Thiocysteine | DB04530 | EXPT00954 |
| 1,6,7,8,9,11A,12,13,14,14A-DECAHYDRO-1,13-DIHYDROXY-6-METHYL-4H-CYCLOPENT[F]OXACYCLOTRIDECIN-4-ONE | DB07348 | - |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030082 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-191-5p | MIMAT0000440 | MIRT045806 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
