HCSGD entry for STK17B
1. General information
| Official gene symbol | STK17B |
|---|---|
| Entrez ID | 9262 |
| Gene full name | serine/threonine kinase 17b |
| Other gene symbols | DRAK2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004672 | Protein kinase activity | IEA ISS | molecular_function |
| GO:0004674 | Protein serine/threonine kinase activity | IDA | molecular_function |
| GO:0005524 | ATP binding | IDA IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005793 | Endoplasmic reticulum-Golgi intermediate compartment | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0006468 | Protein phosphorylation | IDA | biological_process |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0015629 | Actin cytoskeleton | IEA | cellular_component |
| GO:0035556 | Intracellular signal transduction | IDA | biological_process |
| GO:0046777 | Protein autophosphorylation | IEA ISS | biological_process |
| GO:2000271 | Positive regulation of fibroblast apoptotic process | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9483076061 | 0.0552306257 | 0.9999902473 | 0.4430738494 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2536818992 |
| GSE13712_SHEAR | Down | -0.3630833173 |
| GSE13712_STATIC | Down | -0.5647410934 |
| GSE19018 | Down | -0.2767255820 |
| GSE19899_A1 | Up | 0.1568744551 |
| GSE19899_A2 | Down | -0.2660321124 |
| PubMed_21979375_A1 | Down | -0.2109548275 |
| PubMed_21979375_A2 | Down | -0.0414297327 |
| GSE35957 | Down | -0.4637931303 |
| GSE36640 | Down | -0.2685278595 |
| GSE54402 | Down | -0.1856014592 |
| GSE9593 | Down | -0.1444892929 |
| GSE43922 | Down | -0.3141242677 |
| GSE24585 | Up | 0.1361785486 |
| GSE37065 | Down | -0.3313901297 |
| GSE28863_A1 | Up | 0.2542512092 |
| GSE28863_A2 | Up | 0.5357945645 |
| GSE28863_A3 | Down | -0.0767040397 |
| GSE28863_A4 | Up | 0.0101591048 |
| GSE48662 | Down | -0.1411167264 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Quercetin | DB04216 | EXPT02732 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-192-5p | MIMAT0000222 | MIRT026577 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027654 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
