HCSGD entry for MOB1B
1. General information
| Official gene symbol | MOB1B |
|---|---|
| Entrez ID | 92597 |
| Gene full name | MOB kinase activator 1B |
| Other gene symbols | MATS2 MOB4A MOBKL1A |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0019209 | Kinase activator activity | IDA | molecular_function |
| GO:0019900 | Kinase binding | IPI | molecular_function |
| GO:0035329 | Hippo signaling | IDA TAS | biological_process |
| GO:0042325 | Regulation of phosphorylation | IDA | biological_process |
| GO:0042327 | Positive regulation of phosphorylation | IDA | biological_process |
| GO:0043085 | Positive regulation of catalytic activity | IDA | biological_process |
| GO:0046777 | Protein autophosphorylation | IDA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0050790 | Regulation of catalytic activity | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4831565214 | 0.1671051974 | 0.9999902473 | 0.7900890605 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1804053951 |
| GSE13712_SHEAR | Up | 0.4113184479 |
| GSE13712_STATIC | Up | 0.3554416448 |
| GSE19018 | Down | -0.0598922390 |
| GSE19899_A1 | Up | 0.3233947910 |
| GSE19899_A2 | Down | -0.4776531328 |
| PubMed_21979375_A1 | Down | -0.2233741552 |
| PubMed_21979375_A2 | Down | -0.3287191971 |
| GSE35957 | Up | 0.0569478162 |
| GSE36640 | Up | 0.1261897447 |
| GSE54402 | Up | 0.0902943665 |
| GSE9593 | Up | 0.0018174867 |
| GSE43922 | Down | -0.1440779562 |
| GSE24585 | Up | 0.3644797990 |
| GSE37065 | Up | 0.0415246438 |
| GSE28863_A1 | Down | -0.2318752099 |
| GSE28863_A2 | Up | 0.1869499138 |
| GSE28863_A3 | Down | -0.4928122610 |
| GSE28863_A4 | Down | -0.3443490765 |
| GSE48662 | Up | 0.2027847176 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-128-3p | MIMAT0000424 | MIRT022073 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-181a-5p | MIMAT0000256 | MIRT025196 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032390 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-17-5p | MIMAT0000070 | MIRT050791 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
