HCSGD entry for AIMP1
1. General information
| Official gene symbol | AIMP1 |
|---|---|
| Entrez ID | 9255 |
| Gene full name | aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 |
| Other gene symbols | EMAP2 EMAPII HLD3 SCYE1 p43 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000049 | TRNA binding | IDA | molecular_function |
| GO:0001525 | Angiogenesis | IEA | biological_process |
| GO:0001937 | Negative regulation of endothelial cell proliferation | IDA | biological_process |
| GO:0005125 | Cytokine activity | IEA ISS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005615 | Extracellular space | IEA | cellular_component |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005783 | Endoplasmic reticulum | IEA | cellular_component |
| GO:0005794 | Golgi apparatus | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006006 | Glucose metabolic process | IEA | biological_process |
| GO:0006418 | TRNA aminoacylation for protein translation | TAS | biological_process |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0006935 | Chemotaxis | TAS | biological_process |
| GO:0006954 | Inflammatory response | IEA | biological_process |
| GO:0007155 | Cell adhesion | IEA | biological_process |
| GO:0007165 | Signal transduction | NAS | biological_process |
| GO:0007267 | Cell-cell signaling | IDA | biological_process |
| GO:0009611 | Response to wounding | TAS | biological_process |
| GO:0009986 | Cell surface | IDA | cellular_component |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0017101 | Aminoacyl-tRNA synthetase multienzyme complex | IDA | cellular_component |
| GO:0030133 | Transport vesicle | IEA | cellular_component |
| GO:0042803 | Protein homodimerization activity | IDA | molecular_function |
| GO:0050900 | Leukocyte migration | IDA IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9536494624 | 0.0693926523 | 0.9999902473 | 0.4972379967 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1403662855 |
| GSE13712_SHEAR | Up | 0.1135645007 |
| GSE13712_STATIC | Up | 0.3332724875 |
| GSE19018 | Down | -0.5654501017 |
| GSE19899_A1 | Down | -0.1567988606 |
| GSE19899_A2 | Down | -0.1562328048 |
| PubMed_21979375_A1 | Down | -0.9309358460 |
| PubMed_21979375_A2 | Down | -0.5534587352 |
| GSE35957 | Up | 0.3717375355 |
| GSE36640 | Down | -0.0037499528 |
| GSE54402 | Down | -0.2490432801 |
| GSE9593 | Down | -0.1708938159 |
| GSE43922 | Down | -0.0653596349 |
| GSE24585 | Down | -0.3048637305 |
| GSE37065 | Down | -0.2063154553 |
| GSE28863_A1 | Down | -0.0671163496 |
| GSE28863_A2 | Down | -0.0083320074 |
| GSE28863_A3 | Up | 0.0035442837 |
| GSE28863_A4 | Down | -0.0123086790 |
| GSE48662 | Down | -0.2187211653 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020704 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031610 | Proteomics | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
