HCSGD entry for MAGI1
1. General information
| Official gene symbol | MAGI1 |
|---|---|
| Entrez ID | 9223 |
| Gene full name | membrane associated guanylate kinase, WW and PDZ domain containing 1 |
| Other gene symbols | AIP-3 AIP3 BAIAP1 BAP-1 BAP1 MAGI-1 TNRC19 WWP3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0005911 | Cell-cell junction | TAS | cellular_component |
| GO:0005923 | Tight junction | IEA | cellular_component |
| GO:0006461 | Protein complex assembly | NAS | biological_process |
| GO:0007155 | Cell adhesion | TAS | biological_process |
| GO:0007166 | Cell surface receptor signaling pathway | TAS | biological_process |
| GO:0008022 | Protein C-terminus binding | TAS | molecular_function |
| GO:0042995 | Cell projection | IDA | cellular_component |
| GO:0051393 | Alpha-actinin binding | IPI | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9900815015 | 0.0173806694 | 0.9999902473 | 0.2578785795 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3139759171 |
| GSE13712_SHEAR | Up | 0.0573496098 |
| GSE13712_STATIC | Down | -0.0800981632 |
| GSE19018 | Down | -0.1719142778 |
| GSE19899_A1 | Down | -0.1194927190 |
| GSE19899_A2 | Down | -0.1017438560 |
| PubMed_21979375_A1 | Down | -0.8922236864 |
| PubMed_21979375_A2 | Down | -0.1932178334 |
| GSE35957 | Up | 0.3654438727 |
| GSE36640 | Up | 0.0496044777 |
| GSE54402 | Down | -0.1563734188 |
| GSE9593 | Down | -0.2319039324 |
| GSE43922 | Down | -0.4130820425 |
| GSE24585 | Down | -0.0723115158 |
| GSE37065 | Down | -0.4076506694 |
| GSE28863_A1 | Down | -0.0991507588 |
| GSE28863_A2 | Down | -0.5110523707 |
| GSE28863_A3 | Down | -0.8243701529 |
| GSE28863_A4 | Down | -0.0862381726 |
| GSE48662 | Down | -0.2688652539 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017415 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025370 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-24-3p | MIMAT0000080 | MIRT030459 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-324-3p | MIMAT0000762 | MIRT042831 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-141-3p | MIMAT0000432 | NA | hsa-miR-141 | 20005803 | |||
| hsa-miR-200a-3p | MIMAT0000682 | NA | hsa-miR-200a | 20005803 | |||
| hsa-miR-200b-3p | MIMAT0000318 | NA | hsa-miR-200b | 20005803 | |||
| hsa-miR-429 | MIMAT0001536 | NA | hsa-miR-429 | 20005803 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
