HCSGD entry for CD5
1. General information
| Official gene symbol | CD5 |
|---|---|
| Entrez ID | 921 |
| Gene full name | CD5 molecule |
| Other gene symbols | LEU1 T1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004872 | Receptor activity | NAS | molecular_function |
| GO:0004888 | Transmembrane signaling receptor activity | NAS | molecular_function |
| GO:0005044 | Scavenger receptor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0005887 | Integral component of plasma membrane | NAS | cellular_component |
| GO:0008037 | Cell recognition | NAS | biological_process |
| GO:0008283 | Cell proliferation | NAS | biological_process |
| GO:0009897 | External side of plasma membrane | IEA | cellular_component |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0031295 | T cell costimulation | IEA | biological_process |
| GO:0097190 | Apoptotic signaling pathway | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6221933171 | 0.8388010638 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0595217317 |
| GSE13712_SHEAR | Down | -0.0057349839 |
| GSE13712_STATIC | Up | 0.0726632599 |
| GSE19018 | Up | 0.1613583316 |
| GSE19899_A1 | Down | -0.0037888419 |
| GSE19899_A2 | Up | 0.1121530701 |
| PubMed_21979375_A1 | Up | 0.0710736164 |
| PubMed_21979375_A2 | Down | -0.1775399323 |
| GSE35957 | Up | 0.2169043807 |
| GSE36640 | Down | -0.0205309364 |
| GSE54402 | Up | 0.0792566262 |
| GSE9593 | Down | -0.0189037822 |
| GSE43922 | Up | 0.1788720149 |
| GSE24585 | Down | -0.2967382213 |
| GSE37065 | Up | 0.0036819568 |
| GSE28863_A1 | Down | -0.1108417035 |
| GSE28863_A2 | Down | -0.0081620615 |
| GSE28863_A3 | Up | 0.2833513038 |
| GSE28863_A4 | Up | 0.1357231068 |
| GSE48662 | Up | 0.0287191679 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 25931205 | Fluorescence-activated cell sorting (FACS)-purified pro-B cells from fetal liver and adult bone marrow generate B cells with distinct phenotypes: fetal cells generate few IgD(high) B cells and half express CD5, whereas adult cells generate mostly IgD(high) cells and few express CD5 |
| 25931205 | We suggest that Lin28b-promoted B cell development generates many cells expressing CD5 as a consequence of positively selected self-reactivity |
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