HCSGD entry for CD5


1. General information

Official gene symbolCD5
Entrez ID921
Gene full nameCD5 molecule
Other gene symbolsLEU1 T1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004872Receptor activityNASmolecular_function
GO:0004888Transmembrane signaling receptor activityNASmolecular_function
GO:0005044Scavenger receptor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneIDAcellular_component
GO:0005887Integral component of plasma membraneNAScellular_component
GO:0008037Cell recognitionNASbiological_process
GO:0008283Cell proliferationNASbiological_process
GO:0009897External side of plasma membraneIEAcellular_component
GO:0016020MembraneIEAcellular_component
GO:0031295T cell costimulationIEAbiological_process
GO:0097190Apoptotic signaling pathwayIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.62219331710.83880106380.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0595217317
GSE13712_SHEARDown-0.0057349839
GSE13712_STATICUp0.0726632599
GSE19018Up0.1613583316
GSE19899_A1Down-0.0037888419
GSE19899_A2Up0.1121530701
PubMed_21979375_A1Up0.0710736164
PubMed_21979375_A2Down-0.1775399323
GSE35957Up0.2169043807
GSE36640Down-0.0205309364
GSE54402Up0.0792566262
GSE9593Down-0.0189037822
GSE43922Up0.1788720149
GSE24585Down-0.2967382213
GSE37065Up0.0036819568
GSE28863_A1Down-0.1108417035
GSE28863_A2Down-0.0081620615
GSE28863_A3Up0.2833513038
GSE28863_A4Up0.1357231068
GSE48662Up0.0287191679

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

25931205Fluorescence-activated cell sorting (FACS)-purified pro-B cells from fetal liver and adult bone marrow generate B cells with distinct phenotypes: fetal cells generate few IgD(high) B cells and half express CD5, whereas adult cells generate mostly IgD(high) cells and few express CD5
25931205We suggest that Lin28b-promoted B cell development generates many cells expressing CD5 as a consequence of positively selected self-reactivity
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