HCSGD entry for MYLK3

1. General information

Official gene symbolMYLK3
Entrez ID91807
Gene full namemyosin light chain kinase 3
Other gene symbolsMLCK MLCK2 caMLCK
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002528Regulation of vascular permeability involved in acute inflammatory responseIMPbiological_process
GO:0004683Calmodulin-dependent protein kinase activityISSmolecular_function
GO:0004687Myosin light chain kinase activityISSmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005737CytoplasmISScellular_component
GO:0005829CytosolISScellular_component
GO:0006468Protein phosphorylationISSbiological_process
GO:0015629Actin cytoskeletonIEAcellular_component
GO:0045214Sarcomere organizationISSbiological_process
GO:0048769SarcomerogenesisISSbiological_process
GO:0055003Cardiac myofibril assemblyISSbiological_process
GO:0060298Positive regulation of sarcomere organizationISSbiological_process
GO:0071347Cellular response to interleukin-1IMPbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.68577853800.89993814440.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0503236112
GSE13712_SHEARUp0.0737930541
GSE13712_STATICUp0.0999491846
GSE19018Up0.0996664476
GSE19899_A1Up0.0785599356
GSE19899_A2Up0.0480843618
PubMed_21979375_A1Up0.0603561164
PubMed_21979375_A2Up0.0622314912
GSE35957Up0.1290855595
GSE36640Up0.0242163952
GSE54402Down-0.1493000780
GSE9593Up0.0542401864
GSE43922Up0.0276168984
GSE24585Up0.0270266802
GSE37065Down-0.0825728564
GSE28863_A1Up0.0307190538
GSE28863_A2Down-0.0867012417
GSE28863_A3Up0.2566502533
GSE28863_A4Up0.0070582514
GSE48662Down-0.0663442062

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-98-5pMIMAT0000096MIRT027564MicroarrayFunctional MTI (Weak)19088304
Entries Per Page
Displaying Page of
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.