HCSGD entry for ALKBH8

1. General information

Official gene symbolALKBH8
Entrez ID91801
Gene full namealkB, alkylation repair homolog 8 (E. coli)
Other gene symbolsABH8
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000166Nucleotide bindingIEAmolecular_function
GO:0003676Nucleic acid bindingIEAmolecular_function
GO:0003723RNA bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005829CytosolIDAcellular_component
GO:0006974Cellular response to DNA damage stimulusIDAbiological_process
GO:0008168Methyltransferase activityIEAmolecular_function
GO:0015630Microtubule cytoskeletonIDAcellular_component
GO:0016300TRNA (uracil) methyltransferase activityIDAmolecular_function
GO:0016706Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donorsIEAmolecular_function
GO:0030488TRNA methylationIDAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.31644874050.10594598610.99999024730.6231517989

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2382911238
GSE13712_SHEARUp0.3182658958
GSE13712_STATICUp0.5301270431
GSE19018Down-0.6804615259
GSE19899_A1Down-0.1311840181
GSE19899_A2Down-0.4410713192
PubMed_21979375_A1Up0.8131894186
PubMed_21979375_A2Up0.0034267985
GSE35957Down-0.2802264766
GSE36640Down-0.0343829454
GSE54402Up0.0631935722
GSE9593Down-0.0664869701
GSE43922Down-0.0079381528
GSE24585Down-0.8084817540
GSE37065Up0.1344847576
GSE28863_A1Up0.1365209493
GSE28863_A2Up0.1105058712
GSE28863_A3Down-0.7105767965
GSE28863_A4Up0.2529281368
GSE48662Down-0.0416979407

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.