HCSGD entry for IL1RL1
1. General information
| Official gene symbol | IL1RL1 |
|---|---|
| Entrez ID | 9173 |
| Gene full name | interleukin 1 receptor-like 1 |
| Other gene symbols | DER4 FIT-1 IL33R ST2 ST2L ST2V T1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002113 | Interleukin-33 binding | IEA | molecular_function |
| GO:0002114 | Interleukin-33 receptor activity | IEA | molecular_function |
| GO:0002826 | Negative regulation of T-helper 1 type immune response | IEA | biological_process |
| GO:0004896 | Cytokine receptor activity | TAS | molecular_function |
| GO:0004908 | Interleukin-1 receptor activity | IEA | molecular_function |
| GO:0005057 | Receptor signaling protein activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0006955 | Immune response | NAS | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0009897 | External side of plasma membrane | IEA | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0032689 | Negative regulation of interferon-gamma production | IEA | biological_process |
| GO:0032754 | Positive regulation of interleukin-5 production | IEA | biological_process |
| GO:0035556 | Intracellular signal transduction | TAS | biological_process |
| GO:0043032 | Positive regulation of macrophage activation | IEA | biological_process |
| GO:0043124 | Negative regulation of I-kappaB kinase/NF-kappaB signaling | IEA | biological_process |
| GO:0050729 | Positive regulation of inflammatory response | IEA | biological_process |
| GO:0090197 | Positive regulation of chemokine secretion | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0096069754 | 0.9898831541 | 0.2499937870 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0164291691 |
| GSE13712_SHEAR | Up | 1.0984731985 |
| GSE13712_STATIC | Up | 1.6349070825 |
| GSE19018 | Down | -0.0710844599 |
| GSE19899_A1 | Up | 0.1516551653 |
| GSE19899_A2 | Up | 0.2687253129 |
| PubMed_21979375_A1 | Up | 0.1612691575 |
| PubMed_21979375_A2 | Up | 0.3938401774 |
| GSE35957 | Up | 0.0183024707 |
| GSE36640 | Up | 0.1903768966 |
| GSE54402 | Up | 0.3179239663 |
| GSE9593 | Up | 0.2689202519 |
| GSE43922 | Up | 0.7902333632 |
| GSE24585 | Up | 0.3262953992 |
| GSE37065 | Up | 0.2153609555 |
| GSE28863_A1 | Down | -0.1073304030 |
| GSE28863_A2 | Up | 0.8236777814 |
| GSE28863_A3 | Up | 0.1133428949 |
| GSE28863_A4 | Down | -0.0916259265 |
| GSE48662 | Up | 0.1087594796 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029172 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
