HCSGD entry for SLFN11
1. General information
| Official gene symbol | SLFN11 |
|---|---|
| Entrez ID | 91607 |
| Gene full name | schlafen family member 11 |
| Other gene symbols | SLFN8/9 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000049 | TRNA binding | IDA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0051607 | Defense response to virus | IMP | biological_process |
| GO:2000134 | Negative regulation of G1/S transition of mitotic cell cycle | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9990916113 | 0.0000240530 | 0.9999902473 | 0.0085554054 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.5462203270 |
| GSE13712_SHEAR | Down | -0.7916501826 |
| GSE13712_STATIC | Up | 0.0406979163 |
| GSE19018 | Down | -0.8862381963 |
| GSE19899_A1 | Down | -1.6302219522 |
| GSE19899_A2 | Down | -4.7432843605 |
| PubMed_21979375_A1 | Down | -3.1682218982 |
| PubMed_21979375_A2 | Down | -5.9430402423 |
| GSE35957 | Down | -1.2155667824 |
| GSE36640 | Down | -3.4929661375 |
| GSE54402 | Down | -0.7836177833 |
| GSE9593 | Down | -1.3690263335 |
| GSE43922 | Down | -2.7708778488 |
| GSE24585 | Down | -0.0052013533 |
| GSE37065 | Up | 0.0282946994 |
| GSE28863_A1 | Down | -0.3384860846 |
| GSE28863_A2 | Down | -0.0109168719 |
| GSE28863_A3 | Down | -0.0909384338 |
| GSE28863_A4 | Down | -0.0312117317 |
| GSE48662 | Down | -0.8656791851 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-125a-5p | MIMAT0000443 | MIRT045763 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046706 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
