HCSGD entry for PLXNA4
1. General information
| Official gene symbol | PLXNA4 |
|---|---|
| Entrez ID | 91584 |
| Gene full name | plexin A4 |
| Other gene symbols | FAYV2820 PLEXA4 PLXNA4A PLXNA4B PRO34003 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002116 | Semaphorin receptor complex | TAS | cellular_component |
| GO:0005622 | Intracellular | IEA | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0007411 | Axon guidance | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0017154 | Semaphorin receptor activity | IEA | molecular_function |
| GO:0021610 | Facial nerve morphogenesis | IEA | biological_process |
| GO:0021615 | Glossopharyngeal nerve morphogenesis | IEA | biological_process |
| GO:0021636 | Trigeminal nerve morphogenesis | IEA | biological_process |
| GO:0021644 | Vagus nerve morphogenesis | IEA | biological_process |
| GO:0021784 | Postganglionic parasympathetic nervous system development | IEA | biological_process |
| GO:0021793 | Chemorepulsion of branchiomotor axon | IEA | biological_process |
| GO:0021960 | Anterior commissure morphogenesis | IEA | biological_process |
| GO:0048485 | Sympathetic nervous system development | IEA | biological_process |
| GO:0048841 | Regulation of axon extension involved in axon guidance | IEA | biological_process |
| GO:0050923 | Regulation of negative chemotaxis | IEA | biological_process |
| GO:0071526 | Semaphorin-plexin signaling pathway | NAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4865158239 | 0.2797647962 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1406406681 |
| GSE13712_SHEAR | Down | -0.4798387047 |
| GSE13712_STATIC | Down | -0.5625132503 |
| GSE19018 | Up | 0.1342897126 |
| GSE19899_A1 | Up | 0.0666646764 |
| GSE19899_A2 | Up | 0.0298140266 |
| PubMed_21979375_A1 | Up | 0.0926921340 |
| PubMed_21979375_A2 | Down | -0.0340453758 |
| GSE35957 | Down | -0.7333536598 |
| GSE36640 | Up | 0.0678374912 |
| GSE54402 | Up | 0.3301807801 |
| GSE9593 | Down | -0.9280291182 |
| GSE43922 | Up | 0.0254473047 |
| GSE24585 | Down | -0.3351006850 |
| GSE37065 | Up | 0.0678459264 |
| GSE28863_A1 | Up | 0.3026548368 |
| GSE28863_A2 | Up | 0.3356076491 |
| GSE28863_A3 | Up | 0.1821901973 |
| GSE28863_A4 | Down | -0.0184967225 |
| GSE48662 | Down | -0.0267561206 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017313 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-1 | MIMAT0000416 | MIRT023616 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029049 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
