HCSGD entry for SMC3
1. General information
Official gene symbol | SMC3 |
---|---|
Entrez ID | 9126 |
Gene full name | structural maintenance of chromosomes 3 |
Other gene symbols | BAM BMH CDLS3 CSPG6 HCAP SMC3L1 |
Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network

This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
---|---|---|---|
GO:0000278 | Mitotic cell cycle | TAS | biological_process |
GO:0000775 | Chromosome, centromeric region | TAS | cellular_component |
GO:0000785 | Chromatin | IDA | cellular_component |
GO:0000800 | Lateral element | IEA | cellular_component |
GO:0000922 | Spindle pole | IDA | cellular_component |
GO:0003682 | Chromatin binding | IEA | molecular_function |
GO:0003777 | Microtubule motor activity | NAS | molecular_function |
GO:0005515 | Protein binding | IPI | molecular_function |
GO:0005524 | ATP binding | IEA | molecular_function |
GO:0005604 | Basement membrane | TAS | cellular_component |
GO:0005634 | Nucleus | TAS | cellular_component |
GO:0005654 | Nucleoplasm | TAS | cellular_component |
GO:0005694 | Chromosome | TAS | cellular_component |
GO:0005737 | Cytoplasm | IDA | cellular_component |
GO:0005829 | Cytosol | TAS | cellular_component |
GO:0006275 | Regulation of DNA replication | IMP | biological_process |
GO:0006281 | DNA repair | IEA | biological_process |
GO:0007052 | Mitotic spindle organization | IEP | biological_process |
GO:0007062 | Sister chromatid cohesion | IMP NAS | biological_process |
GO:0007067 | Mitosis | IEA | biological_process |
GO:0007126 | Meiosis | IDA | biological_process |
GO:0007165 | Signal transduction | IDA | biological_process |
GO:0008278 | Cohesin complex | NAS | cellular_component |
GO:0016363 | Nuclear matrix | IDA | cellular_component |
GO:0019827 | Stem cell maintenance | IEA | biological_process |
GO:0030893 | Meiotic cohesin complex | IDA | cellular_component |
GO:0032876 | Negative regulation of DNA endoreduplication | IMP | biological_process |
GO:0034991 | Nuclear meiotic cohesin complex | IEA | cellular_component |
GO:0036033 | Mediator complex binding | IEA | molecular_function |
GO:0045502 | Dynein binding | IDA | molecular_function |
GO:0046982 | Protein heterodimerization activity | IPI | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
p-value up | p-value down | FDR up | FDR down |
---|---|---|---|
0.7063023821 | 0.0164103947 | 0.9999902473 | 0.2498195489 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
Data source | Up or down | Log fold change |
---|---|---|
GSE11954 | Down | -0.1533729713 |
GSE13712_SHEAR | Up | 0.0910387197 |
GSE13712_STATIC | Down | -0.2595730475 |
GSE19018 | Up | 0.1743938652 |
GSE19899_A1 | Down | -0.2403005028 |
GSE19899_A2 | Down | -1.0506449822 |
PubMed_21979375_A1 | Down | -0.9541228021 |
PubMed_21979375_A2 | Down | -1.1315511410 |
GSE35957 | Down | -0.5063930927 |
GSE36640 | Down | -1.1451815570 |
GSE54402 | Down | -0.1493145673 |
GSE9593 | Down | -0.2032209359 |
GSE43922 | Down | -0.8104252423 |
GSE24585 | Down | -0.1272984575 |
GSE37065 | Up | 0.0822152587 |
GSE28863_A1 | Up | 0.4078204766 |
GSE28863_A2 | Up | 0.6358298689 |
GSE28863_A3 | Up | 0.3071555553 |
GSE28863_A4 | Up | 0.2722447131 |
GSE48662 | Down | -0.7385159980 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
---|---|---|---|---|---|
hsa-miR-340-5p | MIMAT0004692 | MIRT019626 | Sequencing | Functional MTI (Weak) | 20371350 |
hsa-miR-196a-5p | MIMAT0000226 | MIRT026077 | Sequencing | Functional MTI (Weak) | 20371350 |
hsa-miR-615-3p | MIMAT0003283 | MIRT040180 | CLASH | Functional MTI (Weak) | 23622248 |
hsa-miR-193b-3p | MIMAT0002819 | MIRT041357 | CLASH | Functional MTI (Weak) | 23622248 |
hsa-miR-92a-3p | MIMAT0000092 | MIRT049364 | CLASH | Functional MTI (Weak) | 23622248 |
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