HCSGD entry for TMEM67


1. General information

Official gene symbolTMEM67
Entrez ID91147
Gene full nametransmembrane protein 67
Other gene symbolsJBTS6 MECKELIN MKS3 NPHP11 TNEM67
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005789Endoplasmic reticulum membraneIDAcellular_component
GO:0005813CentrosomeIDAcellular_component
GO:0010826Negative regulation of centrosome duplicationIMPbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0030433ER-associated ubiquitin-dependent protein catabolic processIMPbiological_process
GO:0030659Cytoplasmic vesicle membraneIDAcellular_component
GO:0031005Filamin bindingIPImolecular_function
GO:0036038TCTN-B9D complexISScellular_component
GO:0042384Cilium assemblyIMPbiological_process
GO:0051082Unfolded protein bindingIPImolecular_function
GO:0060170Ciliary membraneIDAcellular_component
GO:0060271Cilium morphogenesisISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.30342733180.67760319520.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1044297753
GSE13712_SHEARDown-0.0681214397
GSE13712_STATICDown-0.0003627132
GSE19018Up0.1847674248
GSE19899_A1Up0.0663614130
GSE19899_A2Down-0.0056007943
PubMed_21979375_A1Down-0.0651474043
PubMed_21979375_A2Up0.1317255722
GSE35957Up0.0018613396
GSE36640Up0.2632858830
GSE54402Up0.1337669208
GSE9593Down-0.0221288372
GSE43922Up0.4240408352
GSE24585Up0.6270334879
GSE37065Up0.2615715963
GSE28863_A1Down-0.0682623822
GSE28863_A2Up0.3133347421
GSE28863_A3Down-0.5791625135
GSE28863_A4Down-0.3270454463
GSE48662Down-0.1634805047

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.