HCSGD entry for MTMR4
1. General information
| Official gene symbol | MTMR4 |
|---|---|
| Entrez ID | 9110 |
| Gene full name | myotubularin related protein 4 |
| Other gene symbols | FYVE-DSP2 ZFYVE11 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004722 | Protein serine/threonine phosphatase activity | TAS | molecular_function |
| GO:0004725 | Protein tyrosine phosphatase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006470 | Protein dephosphorylation | TAS | biological_process |
| GO:0006644 | Phospholipid metabolic process | TAS | biological_process |
| GO:0006661 | Phosphatidylinositol biosynthetic process | TAS | biological_process |
| GO:0007179 | Transforming growth factor beta receptor signaling pathway | TAS | biological_process |
| GO:0014894 | Response to denervation involved in regulation of muscle adaptation | IEA | biological_process |
| GO:0016791 | Phosphatase activity | IEA | molecular_function |
| GO:0030512 | Negative regulation of transforming growth factor beta receptor signaling pathway | TAS | biological_process |
| GO:0031901 | Early endosome membrane | TAS | cellular_component |
| GO:0035335 | Peptidyl-tyrosine dephosphorylation | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6662910870 | 0.0091828958 | 0.9999902473 | 0.1892740799 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3455255241 |
| GSE13712_SHEAR | Down | -0.2703642110 |
| GSE13712_STATIC | Up | 0.3843051997 |
| GSE19018 | Up | 0.0921163687 |
| GSE19899_A1 | Down | -0.9700845048 |
| GSE19899_A2 | Down | -1.1612394045 |
| PubMed_21979375_A1 | Down | -1.8918555643 |
| PubMed_21979375_A2 | Down | -1.0460550567 |
| GSE35957 | Down | -0.6996379160 |
| GSE36640 | Down | -1.7061590163 |
| GSE54402 | Up | 0.4367950508 |
| GSE9593 | Up | 0.0418604391 |
| GSE43922 | Down | -0.9599626366 |
| GSE24585 | Up | 0.0535929190 |
| GSE37065 | Down | -0.0742636566 |
| GSE28863_A1 | Up | 0.6362919720 |
| GSE28863_A2 | Up | 0.8588837272 |
| GSE28863_A3 | Down | -0.3107081087 |
| GSE28863_A4 | Down | -0.0995413116 |
| GSE48662 | Down | -0.1853161275 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-130b-3p | MIMAT0000691 | MIRT020319 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-103a-3p | MIMAT0000101 | MIRT027212 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041608 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-125b-5p | MIMAT0000423 | MIRT046004 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
