HCSGD entry for USP6

1. General information

Official gene symbolUSP6
Entrez ID9098
Gene full nameubiquitin specific peptidase 6 (Tre-2 oncogene)
Other gene symbolsHRP1 TRE17 TRE2 Tre-2 USP6-short
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003676Nucleic acid bindingTASmolecular_function
GO:0004197Cysteine-type endopeptidase activityTASmolecular_function
GO:0004221Ubiquitin thiolesterase activityIEAmolecular_function
GO:0004843Ubiquitin-specific protease activityIDAmolecular_function
GO:0005097Rab GTPase activator activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005516Calmodulin bindingIPImolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005764LysosomeTAScellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0006464Cellular protein modification processNASbiological_process
GO:0006511Ubiquitin-dependent protein catabolic processIEAbiological_process
GO:0016579Protein deubiquitinationIDAbiological_process
GO:0055037Recycling endosomeIDAcellular_component
GO:0060627Regulation of vesicle-mediated transportIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.50075624790.95514743740.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954--
GSE13712_SHEAR--
GSE13712_STATIC--
GSE19018--
GSE19899_A1--
GSE19899_A2--
PubMed_21979375_A1--
PubMed_21979375_A2--
GSE35957--
GSE36640--
GSE54402--
GSE9593--
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1Up0.2700054979
GSE28863_A2Up0.3041948039
GSE28863_A3Down-0.1427553489
GSE28863_A4Up0.2520659931
GSE48662Down-0.2004769366

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT029644MicroarrayFunctional MTI (Weak)19088304
hsa-miR-423-5pMIMAT0004748MIRT038017CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.