HCSGD entry for TBX18

1. General information

Official gene symbolTBX18
Entrez ID9096
Gene full nameT-box 18
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterISSbiological_process
GO:0000976Transcription regulatory region sequence-specific DNA bindingISSmolecular_function
GO:0001106RNA polymerase II transcription corepressor activityISSmolecular_function
GO:0001756SomitogenesisIEAbiological_process
GO:0003163Sinoatrial node developmentIEAbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005634NucleusIEA ISScellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006357Regulation of transcription from RNA polymerase II promoterISSbiological_process
GO:0006366Transcription from RNA polymerase II promoterISSbiological_process
GO:0007605Sensory perception of soundIEAbiological_process
GO:0009948Anterior/posterior axis specificationIEAbiological_process
GO:0016331Morphogenesis of embryonic epitheliumIEAbiological_process
GO:0022409Positive regulation of cell-cell adhesionIEAbiological_process
GO:0042803Protein homodimerization activityISSmolecular_function
GO:0046982Protein heterodimerization activityISSmolecular_function
GO:0050679Positive regulation of epithelial cell proliferationIEAbiological_process
GO:0051145Smooth muscle cell differentiationIEAbiological_process
GO:0060829Negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formationISSbiological_process
GO:0090103Cochlea morphogenesisIEAbiological_process
GO:2000729Positive regulation of mesenchymal cell proliferation involved in ureter developmentIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.55161072530.51694759320.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1602815125
GSE13712_SHEARUp0.5123897316
GSE13712_STATICUp0.3185510865
GSE19018Up0.0824887233
GSE19899_A1Up0.0107150401
GSE19899_A2Down-0.0800456289
PubMed_21979375_A1Up0.0847682003
PubMed_21979375_A2Up0.0623769330
GSE35957Up0.1207311154
GSE36640Up0.1863675207
GSE54402Down-0.0144103551
GSE9593Up0.0046220431
GSE43922Up0.0136828369
GSE24585Down-0.5176934683
GSE37065Down-0.1000481748
GSE28863_A1Up0.3692304596
GSE28863_A2Down-0.0664618859
GSE28863_A3Up0.0563297921
GSE28863_A4Down-0.0756316139
GSE48662Down-0.0404132787

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-1226-3pMIMAT0005577MIRT036442CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.