HCSGD entry for SEC11C
1. General information
| Official gene symbol | SEC11C |
|---|---|
| Entrez ID | 90701 |
| Gene full name | SEC11 homolog C (S. cerevisiae) |
| Other gene symbols | SEC11L3 SPC21 SPCS4C |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0006412 | Translation | TAS | biological_process |
| GO:0006465 | Signal peptide processing | IEA | biological_process |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | TAS | biological_process |
| GO:0008236 | Serine-type peptidase activity | IEA | molecular_function |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
| GO:0050796 | Regulation of insulin secretion | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0156254930 | 0.9238718476 | 0.3097896084 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.6345827962 |
| GSE13712_SHEAR | Down | -0.1746316756 |
| GSE13712_STATIC | Up | 0.2390927113 |
| GSE19018 | Up | 0.2354141362 |
| GSE19899_A1 | Up | 0.1387161454 |
| GSE19899_A2 | Up | 0.5171973898 |
| PubMed_21979375_A1 | Up | 0.8345408773 |
| PubMed_21979375_A2 | Up | 0.5815643248 |
| GSE35957 | Down | -0.7806564281 |
| GSE36640 | Up | 0.8733094419 |
| GSE54402 | Up | 0.1005978475 |
| GSE9593 | Up | 0.4995684171 |
| GSE43922 | Up | 0.3160536076 |
| GSE24585 | Down | -0.3754644874 |
| GSE37065 | Up | 0.8549474108 |
| GSE28863_A1 | Down | -0.2908033006 |
| GSE28863_A2 | Up | 0.1948291286 |
| GSE28863_A3 | Down | -0.1454992536 |
| GSE28863_A4 | Up | 0.1320518156 |
| GSE48662 | Up | 0.0861785570 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-30a-5p | MIMAT0000087 | MIRT005192 | pSILAC//Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-1 | MIMAT0000416 | MIRT023588 | Proteomics | Functional MTI (Weak) | 18668040 |
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