HCSGD entry for DOK2
1. General information
| Official gene symbol | DOK2 |
|---|---|
| Entrez ID | 9046 |
| Gene full name | docking protein 2, 56kDa |
| Other gene symbols | p56DOK p56dok-2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005057 | Receptor signaling protein activity | IEA | molecular_function |
| GO:0005068 | Transmembrane receptor protein tyrosine kinase adaptor activity | IEA | molecular_function |
| GO:0005158 | Insulin receptor binding | IEA | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0007166 | Cell surface receptor signaling pathway | TAS | biological_process |
| GO:0007265 | Ras protein signal transduction | IEA | biological_process |
| GO:0007596 | Blood coagulation | TAS | biological_process |
| GO:0050900 | Leukocyte migration | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6706458455 | 0.6751642415 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1109816083 |
| GSE13712_SHEAR | Down | -0.0317625574 |
| GSE13712_STATIC | Up | 0.2315292113 |
| GSE19018 | Down | -0.0674047545 |
| GSE19899_A1 | Up | 0.1070217076 |
| GSE19899_A2 | Up | 0.1751588828 |
| PubMed_21979375_A1 | Down | -0.0874159880 |
| PubMed_21979375_A2 | Down | -0.1747197521 |
| GSE35957 | Up | 0.2403097787 |
| GSE36640 | Down | -0.0656739593 |
| GSE54402 | Up | 0.0159413697 |
| GSE9593 | Up | 0.2975643181 |
| GSE43922 | Down | -0.0558316378 |
| GSE24585 | Up | 0.1045738150 |
| GSE37065 | Down | -0.0370312223 |
| GSE28863_A1 | Down | -0.2204173684 |
| GSE28863_A2 | Down | -0.1327488344 |
| GSE28863_A3 | Up | 0.2160586567 |
| GSE28863_A4 | Up | 0.0973675883 |
| GSE48662 | Up | 0.0123028818 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041270 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
