HCSGD entry for PKD2L1

1. General information

Official gene symbolPKD2L1
Entrez ID9033
Gene full namepolycystic kidney disease 2-like 1
Other gene symbolsPCL PKD2L PKDL TRPP3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001581Detection of chemical stimulus involved in sensory perception of sour tasteISSbiological_process
GO:0005227Calcium activated cation channel activityIDAmolecular_function
GO:0005261Cation channel activityIDAmolecular_function
GO:0005262Calcium channel activityIBAmolecular_function
GO:0005272Sodium channel activityIDAmolecular_function
GO:0005509Calcium ion bindingISSmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005783Endoplasmic reticulumISScellular_component
GO:0005886Plasma membraneIMPcellular_component
GO:0006812Cation transportISSbiological_process
GO:0007165Signal transductionISSbiological_process
GO:0007186G-protein coupled receptor signaling pathwayISSbiological_process
GO:0008092Cytoskeletal protein bindingIPImolecular_function
GO:0008324Cation transmembrane transporter activityISSmolecular_function
GO:0009986Cell surfaceISScellular_component
GO:0015269Calcium-activated potassium channel activityIDAmolecular_function
GO:0016021Integral component of membraneNAScellular_component
GO:0033040Sour taste receptor activityISSmolecular_function
GO:0035725Sodium ion transmembrane transportIDAbiological_process
GO:0042802Identical protein bindingISSmolecular_function
GO:0043231Intracellular membrane-bounded organelleIDAcellular_component
GO:0050982Detection of mechanical stimulusIBAbiological_process
GO:0051371Muscle alpha-actinin bindingIPImolecular_function
GO:0051393Alpha-actinin bindingIPImolecular_function
GO:0070588Calcium ion transmembrane transportIBAbiological_process
GO:0071468Cellular response to acidityISSbiological_process
GO:0071805Potassium ion transmembrane transportIDAbiological_process
GO:0072511Divalent inorganic cation transportIBAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.87538811980.42173882450.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2827254453
GSE13712_SHEARDown-0.1759794920
GSE13712_STATICDown-0.2115711353
GSE19018Up0.0618475612
GSE19899_A1Down-0.0351147484
GSE19899_A2Down-0.0398790431
PubMed_21979375_A1Down-0.1922462533
PubMed_21979375_A2Down-0.2357175932
GSE35957Up0.1698468017
GSE36640Up0.0713134721
GSE54402Down-0.1018931057
GSE9593Up0.1665450168
GSE43922Up0.0165046105
GSE24585Down-0.1291687094
GSE37065Down-0.1121197445
GSE28863_A1Up0.0071065156
GSE28863_A2Up0.0107468206
GSE28863_A3Up0.2356776347
GSE28863_A4Up0.0657592792
GSE48662Up0.2631894193

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018375MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.