HCSGD entry for TNFSF18

1. General information

Official gene symbolTNFSF18
Entrez ID8995
Gene full nametumor necrosis factor (ligand) superfamily, member 18
Other gene symbolsAITRL GITRL TL6 hGITRL
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002309T cell proliferation involved in immune responseISSbiological_process
GO:0005102Receptor bindingTASmolecular_function
GO:0005125Cytokine activityIEAmolecular_function
GO:0005164Tumor necrosis factor receptor bindingIEAmolecular_function
GO:0005615Extracellular spaceIEAcellular_component
GO:0005886Plasma membraneIEAcellular_component
GO:0007165Signal transductionTASbiological_process
GO:0007267Cell-cell signalingTASbiological_process
GO:0009986Cell surfaceISScellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0032813Tumor necrosis factor receptor superfamily bindingISSmolecular_function
GO:0033209Tumor necrosis factor-mediated signaling pathwayISSbiological_process
GO:0042129Regulation of T cell proliferationISSbiological_process
GO:0043066Negative regulation of apoptotic processTASbiological_process
GO:0051092Positive regulation of NF-kappaB transcription factor activityISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.01223831540.98119138710.27602802061.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0427318163
GSE13712_SHEARUp0.8976785301
GSE13712_STATICUp1.0786799571
GSE19018Down-0.0421221640
GSE19899_A1Up0.0633062437
GSE19899_A2Up0.1848652866
PubMed_21979375_A1Down-0.0100013267
PubMed_21979375_A2Down-0.0756531175
GSE35957Up0.2293231078
GSE36640Up2.6926041136
GSE54402Down-0.1003113486
GSE9593Up0.1832108470
GSE43922Up0.1438107405
GSE24585Up0.0420061130
GSE37065Up0.9960982613
GSE28863_A1Up0.3704844497
GSE28863_A2Up0.7020176877
GSE28863_A3Up0.1519634903
GSE28863_A4Up0.1543710454
GSE48662Up0.0078727424

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.