HCSGD entry for ATP6V0E1
1. General information
| Official gene symbol | ATP6V0E1 |
|---|---|
| Entrez ID | 8992 |
| Gene full name | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 |
| Other gene symbols | ATP6H ATP6V0E M9.2 Vma21 Vma21p |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005215 | Transporter activity | NAS | molecular_function |
| GO:0006200 | ATP catabolic process | ISS TAS | biological_process |
| GO:0006879 | Cellular iron ion homeostasis | TAS | biological_process |
| GO:0007035 | Vacuolar acidification | ISS | biological_process |
| GO:0008152 | Metabolic process | ISS TAS | biological_process |
| GO:0008286 | Insulin receptor signaling pathway | TAS | biological_process |
| GO:0010008 | Endosome membrane | TAS | cellular_component |
| GO:0015078 | Hydrogen ion transmembrane transporter activity | IEA | molecular_function |
| GO:0015991 | ATP hydrolysis coupled proton transport | IEA | biological_process |
| GO:0015992 | Proton transport | TAS | biological_process |
| GO:0016020 | Membrane | TAS | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016049 | Cell growth | IGI | biological_process |
| GO:0030670 | Phagocytic vesicle membrane | TAS | cellular_component |
| GO:0033179 | Proton-transporting V-type ATPase, V0 domain | IEA | cellular_component |
| GO:0033572 | Transferrin transport | TAS | biological_process |
| GO:0042625 | ATPase activity, coupled to transmembrane movement of ions | ISS | molecular_function |
| GO:0043200 | Response to amino acid | IEA | biological_process |
| GO:0046961 | Proton-transporting ATPase activity, rotational mechanism | TAS | molecular_function |
| GO:0051701 | Interaction with host | TAS | biological_process |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
| GO:0090382 | Phagosome maturation | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0631045591 | 0.9761662969 | 0.5429963867 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4083005118 |
| GSE13712_SHEAR | Down | -0.1673411554 |
| GSE13712_STATIC | Up | 0.0315197098 |
| GSE19018 | Up | 0.0056268905 |
| GSE19899_A1 | Up | 0.2012047376 |
| GSE19899_A2 | Up | 0.1145990253 |
| PubMed_21979375_A1 | Up | 0.3053017256 |
| PubMed_21979375_A2 | Up | 0.0495413480 |
| GSE35957 | Up | 0.6871808788 |
| GSE36640 | Up | 1.0714496356 |
| GSE54402 | Up | 0.0523727283 |
| GSE9593 | Up | 0.4943256813 |
| GSE43922 | Up | 0.0194851799 |
| GSE24585 | Up | 0.2200649819 |
| GSE37065 | Up | 0.3233656248 |
| GSE28863_A1 | Down | -0.0976777604 |
| GSE28863_A2 | Up | 0.0881018973 |
| GSE28863_A3 | Down | -0.1155787576 |
| GSE28863_A4 | Down | -0.0437039722 |
| GSE48662 | Up | 0.1159855560 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT003839 | Microarray//qRT-PCR | Functional MTI (Weak) | 16549876 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT003839 | Microarray | Functional MTI (Weak) | 15685193 |
| hsa-miR-132-3p | MIMAT0000426 | MIRT021775 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-218-5p | MIMAT0000275 | MIRT024214 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-181a-5p | MIMAT0000256 | MIRT025129 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-15b-5p | MIMAT0000417 | MIRT046421 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT051167 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
