HCSGD entry for UBE3B


1. General information

Official gene symbolUBE3B
Entrez ID89910
Gene full nameubiquitin protein ligase E3B
Other gene symbolsBPIDS
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004842Ubiquitin-protein ligase activityIBA IEAmolecular_function
GO:0005634NucleusIBAcellular_component
GO:0005737CytoplasmIBAcellular_component
GO:0042787Protein ubiquitination involved in ubiquitin-dependent protein catabolic processIBAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.14329358690.93439340070.75811668341.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0815502468
GSE13712_SHEARUp0.2329500982
GSE13712_STATICUp0.1091693369
GSE19018Up0.0320771796
GSE19899_A1Up0.0268446193
GSE19899_A2Up0.3189193294
PubMed_21979375_A1Up0.2578009269
PubMed_21979375_A2Up0.2273484556
GSE35957Down-0.0216322888
GSE36640Up0.0006754212
GSE54402Up0.0460210278
GSE9593Up0.0357201954
GSE43922Up0.0700598181
GSE24585Up0.6350255415
GSE37065Down-0.0791843783
GSE28863_A1Up0.6574791941
GSE28863_A2Up0.3620380451
GSE28863_A3Down-0.4200402361
GSE28863_A4Down-0.0882127683
GSE48662Up0.1802016813

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-93-5pMIMAT0000093MIRT028096SequencingFunctional MTI (Weak)20371350
hsa-miR-760MIMAT0004957MIRT036735CLASHFunctional MTI (Weak)23622248
hsa-miR-106b-3pMIMAT0004672MIRT038562CLASHFunctional MTI (Weak)23622248
hsa-miR-324-3pMIMAT0000762MIRT042897CLASHFunctional MTI (Weak)23622248
hsa-miR-15b-5pMIMAT0000417MIRT046488CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.