HCSGD entry for TRPA1

1. General information

Official gene symbolTRPA1
Entrez ID8989
Gene full nametransient receptor potential cation channel, subfamily A, member 1
Other gene symbolsANKTM1 FEPS
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005216Ion channel activityIEAmolecular_function
GO:0005262Calcium channel activityIEAmolecular_function
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006811Ion transportTASbiological_process
GO:0009409Response to coldIEAbiological_process
GO:0015267Channel activityTASmolecular_function
GO:0016021Integral component of membraneIEAcellular_component
GO:0032421Stereocilium bundleIEAcellular_component
GO:0042493Response to drugIEAbiological_process
GO:0042542Response to hydrogen peroxideIEAbiological_process
GO:0048265Response to painIEAbiological_process
GO:0050955ThermoceptionIEAbiological_process
GO:0050966Detection of mechanical stimulus involved in sensory perception of painIEAbiological_process
GO:0050968Detection of chemical stimulus involved in sensory perception of painIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.02581128000.09121498800.37642088640.5744040191

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0998725823
GSE13712_SHEARDown-0.0606009335
GSE13712_STATICUp0.1075250283
GSE19018Down-3.3157532023
GSE19899_A1Up1.1020284783
GSE19899_A2Down-0.9799220816
PubMed_21979375_A1Up0.7396629366
PubMed_21979375_A2Up0.6185183384
GSE35957Up0.1938178843
GSE36640Up2.6383378765
GSE54402Down-0.7023924450
GSE9593Down-0.1919952921
GSE43922Up2.0319887770
GSE24585Down-0.1924461110
GSE37065Up1.0009420836
GSE28863_A1Down-0.1177825278
GSE28863_A2Up0.2417224602
GSE28863_A3Up0.0978573885
GSE28863_A4Down-0.1320088249
GSE48662Up0.0278140103

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-1MIMAT0000416MIRT023904MicroarrayFunctional MTI (Weak)18668037
hsa-miR-7-5pMIMAT0000252MIRT025846MicroarrayFunctional MTI (Weak)17612493
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.