HCSGD entry for PLCZ1
1. General information
| Official gene symbol | PLCZ1 |
|---|---|
| Entrez ID | 89869 |
| Gene full name | phospholipase C, zeta 1 |
| Other gene symbols | NYD-SP27 PLC-zeta-1 PLCzeta |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004435 | Phosphatidylinositol phospholipase C activity | IEA | molecular_function |
| GO:0004629 | Phospholipase C activity | IEA | molecular_function |
| GO:0004871 | Signal transducer activity | IEA | molecular_function |
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005829 | Cytosol | IEA TAS | cellular_component |
| GO:0006629 | Lipid metabolic process | IEA | biological_process |
| GO:0006816 | Calcium ion transport | IEA | biological_process |
| GO:0007275 | Multicellular organismal development | IEA | biological_process |
| GO:0007343 | Egg activation | IEA | biological_process |
| GO:0016042 | Lipid catabolic process | IEA | biological_process |
| GO:0035556 | Intracellular signal transduction | IEA | biological_process |
| GO:0043647 | Inositol phosphate metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0048471 | Perinuclear region of cytoplasm | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5372413966 | 0.7703836176 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1391840941 |
| GSE13712_SHEAR | Down | -0.0175047396 |
| GSE13712_STATIC | Down | -0.0324008127 |
| GSE19018 | Down | -0.0098574981 |
| GSE19899_A1 | Down | -0.0774950278 |
| GSE19899_A2 | Up | 0.4895917762 |
| PubMed_21979375_A1 | Up | 0.4239906963 |
| PubMed_21979375_A2 | Up | 0.5632536602 |
| GSE35957 | Down | -0.0989234044 |
| GSE36640 | Down | -0.1473882100 |
| GSE54402 | Up | 0.1735791059 |
| GSE9593 | Up | 0.0893650682 |
| GSE43922 | Up | 0.0090037519 |
| GSE24585 | Down | -0.2815800484 |
| GSE37065 | Down | -0.0674134780 |
| GSE28863_A1 | Down | -0.0298411352 |
| GSE28863_A2 | Down | -0.1168430148 |
| GSE28863_A3 | Up | 0.1266312857 |
| GSE28863_A4 | Down | -0.0314340090 |
| GSE48662 | Up | 0.0495910536 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
