HCSGD entry for LMLN
1. General information
| Official gene symbol | LMLN |
|---|---|
| Entrez ID | 89782 |
| Gene full name | leishmanolysin-like (metallopeptidase M8 family) |
| Other gene symbols | GP63 INV IX14 MSP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004222 | Metalloendopeptidase activity | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005811 | Lipid particle | IEA | cellular_component |
| GO:0005925 | Focal adhesion | IDA | cellular_component |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0007067 | Mitosis | IEA | biological_process |
| GO:0007155 | Cell adhesion | IEA | biological_process |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0316661943 | 0.8059104707 | 0.4111918599 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2694379441 |
| GSE13712_SHEAR | Down | -0.2715388333 |
| GSE13712_STATIC | Up | 0.0053027720 |
| GSE19018 | Up | 0.3524961418 |
| GSE19899_A1 | Up | 0.1686852251 |
| GSE19899_A2 | Up | 0.5662011983 |
| PubMed_21979375_A1 | Up | 0.1780423217 |
| PubMed_21979375_A2 | Up | 0.4043577544 |
| GSE35957 | Down | -0.3321456795 |
| GSE36640 | Up | 1.2700413567 |
| GSE54402 | Up | 0.3797141831 |
| GSE9593 | Up | 0.2397140160 |
| GSE43922 | Up | 0.4234090750 |
| GSE24585 | Up | 0.9997369416 |
| GSE37065 | Up | 0.1649561229 |
| GSE28863_A1 | Down | -0.0242272584 |
| GSE28863_A2 | Up | 0.3583729896 |
| GSE28863_A3 | Down | -0.4463344720 |
| GSE28863_A4 | Down | -0.4106458324 |
| GSE48662 | Up | 0.1504065421 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018194 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026528 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051516 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
