HCSGD entry for MGAM
1. General information
| Official gene symbol | MGAM |
|---|---|
| Entrez ID | 8972 |
| Gene full name | maltase-glucoamylase (alpha-glucosidase) |
| Other gene symbols | MG MGA |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003824 | Catalytic activity | TAS | molecular_function |
| GO:0004339 | Glucan 1,4-alpha-glucosidase activity | IEA | molecular_function |
| GO:0004553 | Hydrolase activity, hydrolyzing O-glycosyl compounds | IEA | molecular_function |
| GO:0004558 | Alpha-glucosidase activity | IEA TAS | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005975 | Carbohydrate metabolic process | IEA TAS | biological_process |
| GO:0005983 | Starch catabolic process | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016160 | Amylase activity | IEA | molecular_function |
| GO:0016324 | Apical plasma membrane | IEA | cellular_component |
| GO:0030246 | Carbohydrate binding | IEA | molecular_function |
| GO:0032450 | Maltose alpha-glucosidase activity | IEA | molecular_function |
| GO:0044245 | Polysaccharide digestion | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0946478211 | 0.4142652027 | 0.6445602329 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1169807230 |
| GSE13712_SHEAR | Down | -0.1029276500 |
| GSE13712_STATIC | Up | 0.0978933680 |
| GSE19018 | Up | 0.0735842681 |
| GSE19899_A1 | Down | -0.0012235047 |
| GSE19899_A2 | Up | 0.2800889442 |
| PubMed_21979375_A1 | Up | 0.3016279611 |
| PubMed_21979375_A2 | Up | 0.3078066565 |
| GSE35957 | Up | 2.4047854246 |
| GSE36640 | Up | 0.6099982158 |
| GSE54402 | Down | -0.0603089575 |
| GSE9593 | Up | 0.4821165918 |
| GSE43922 | Up | 0.0488694870 |
| GSE24585 | Down | -0.0107860172 |
| GSE37065 | Down | -0.1367970186 |
| GSE28863_A1 | Up | 0.0613954975 |
| GSE28863_A2 | Down | -0.5522100465 |
| GSE28863_A3 | Down | -0.3827151508 |
| GSE28863_A4 | Down | -0.0979742159 |
| GSE48662 | Down | -0.2302439489 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
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- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 20362703 | Here, we demonstrate that FGFR3 signaling is also capable of inducing premature senescence in chondrocytes, manifested as reversible, ERK-dependent growth arrest accompanied by alteration of cellular shape, loss of the extracellular matrix, upregulation of senescence markers (alpha-GLUCOSIDASE, FIBRONECTIN, CAVEOLIN 1, LAMIN A, SM22alpha and TIMP 1), and induction of senescence-associated beta-GALACTOSIDASE activity |
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