HCSGD entry for TOP3B
1. General information
| Official gene symbol | TOP3B |
|---|---|
| Entrez ID | 8940 |
| Gene full name | topoisomerase (DNA) III beta |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000793 | Condensed chromosome | IEA | cellular_component |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003916 | DNA topoisomerase activity | TAS | molecular_function |
| GO:0003917 | DNA topoisomerase type I activity | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | TAS | cellular_component |
| GO:0005694 | Chromosome | IEA | cellular_component |
| GO:0006265 | DNA topological change | IEA | biological_process |
| GO:0007059 | Chromosome segregation | IEA | biological_process |
Entries Per Page
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1966488089 | 0.8890614224 | 0.8580890749 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0407349338 |
| GSE13712_SHEAR | Up | 0.0008203769 |
| GSE13712_STATIC | Up | 0.0052309122 |
| GSE19018 | Down | -0.0677313559 |
| GSE19899_A1 | Up | 0.0120633122 |
| GSE19899_A2 | Up | 0.2851793916 |
| PubMed_21979375_A1 | Up | 0.1770286441 |
| PubMed_21979375_A2 | Up | 0.4068711235 |
| GSE35957 | Down | -0.0795566254 |
| GSE36640 | Up | 0.0350083236 |
| GSE54402 | Up | 0.0374924701 |
| GSE9593 | Up | 0.1720573558 |
| GSE43922 | Up | 0.2117983885 |
| GSE24585 | Down | -0.1136580650 |
| GSE37065 | Down | -0.0710261587 |
| GSE28863_A1 | Up | 0.2366354201 |
| GSE28863_A2 | Up | 0.1441286283 |
| GSE28863_A3 | Down | -0.0324246733 |
| GSE28863_A4 | Up | 0.0778384070 |
| GSE48662 | Up | 0.0408568497 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
