HCSGD entry for FOXH1

1. General information

Official gene symbolFOXH1
Entrez ID8928
Gene full nameforkhead box H1
Other gene symbolsFAST-1 FAST1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIBAbiological_process
GO:0001104RNA polymerase II transcription cofactor activityIEAmolecular_function
GO:0001190RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcriptionIEAmolecular_function
GO:0001205RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcriptionIEAmolecular_function
GO:0001568Blood vessel developmentIBAbiological_process
GO:0001947Heart loopingIBAbiological_process
GO:0003139Secondary heart field specificationIEAbiological_process
GO:0003146Heart joggingIBAbiological_process
GO:0003151Outflow tract morphogenesisIEAbiological_process
GO:0003215Cardiac right ventricle morphogenesisIEAbiological_process
GO:0003222Ventricular trabecula myocardium morphogenesisIEAbiological_process
GO:0003677DNA bindingIDAmolecular_function
GO:0003690Double-stranded DNA bindingIBAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityIDA NASmolecular_function
GO:0003705RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activityIBAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIC IDAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005667Transcription factor complexIDAcellular_component
GO:0006366Transcription from RNA polymerase II promoterIBAbiological_process
GO:0007179Transforming growth factor beta receptor signaling pathwayISS TASbiological_process
GO:0008134Transcription factor bindingIBAmolecular_function
GO:0008301DNA binding, bendingIBAmolecular_function
GO:0010159Specification of organ positionIBAbiological_process
GO:0019904Protein domain specific bindingIPImolecular_function
GO:0021508Floor plate formationIBAbiological_process
GO:0032444Activin responsive factor complexIDAcellular_component
GO:0033147Negative regulation of intracellular estrogen receptor signaling pathwayIDAbiological_process
GO:0035054Embryonic heart tube anterior/posterior pattern specificationIBAbiological_process
GO:0035909Aorta morphogenesisIEAbiological_process
GO:0042074Cell migration involved in gastrulationIBAbiological_process
GO:0043565Sequence-specific DNA bindingIDAmolecular_function
GO:0044212Transcription regulatory region DNA bindingISSmolecular_function
GO:0045893Positive regulation of transcription, DNA-templatedIDAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0048318Axial mesoderm developmentIBAbiological_process
GO:0050681Androgen receptor bindingIPImolecular_function
GO:0060766Negative regulation of androgen receptor signaling pathwayIDAbiological_process
GO:0070410Co-SMAD bindingIMPmolecular_function
GO:0070412R-SMAD bindingIMP IPImolecular_function
GO:1900164Nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetryNASbiological_process
GO:2000824Negative regulation of androgen receptor activityIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.22897162720.91825505870.91145499771.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0614776521
GSE13712_SHEARDown-0.0280514298
GSE13712_STATICUp0.0110274761
GSE19018Up0.0809188089
GSE19899_A1Down-0.0611822346
GSE19899_A2Up0.1458844045
PubMed_21979375_A1Up0.3957132079
PubMed_21979375_A2Down-0.1171741926
GSE35957Up0.0379671655
GSE36640Up0.4981619089
GSE54402Down-0.0726438839
GSE9593Up0.2034820654
GSE43922Up0.1869233055
GSE24585Down-0.1385721606
GSE37065Up0.0446209300
GSE28863_A1Down-0.0439508750
GSE28863_A2Down-0.1634888653
GSE28863_A3Up0.5085150702
GSE28863_A4Up0.0236320050
GSE48662Up0.7664410065

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.