HCSGD entry for CCNC
1. General information
| Official gene symbol | CCNC |
|---|---|
| Entrez ID | 892 |
| Gene full name | cyclin C |
| Other gene symbols | CycC |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000079 | Regulation of cyclin-dependent protein serine/threonine kinase activity | IEA | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0006351 | Transcription, DNA-templated | TAS | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0006367 | Transcription initiation from RNA polymerase II promoter | TAS | biological_process |
| GO:0007179 | Transforming growth factor beta receptor signaling pathway | TAS | biological_process |
| GO:0007219 | Notch signaling pathway | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016591 | DNA-directed RNA polymerase II, holoenzyme | IEA | cellular_component |
| GO:0016592 | Mediator complex | IEA | cellular_component |
| GO:0019901 | Protein kinase binding | IEA | molecular_function |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9861191520 | 0.0560022454 | 0.9999902473 | 0.4446561388 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0249277412 |
| GSE13712_SHEAR | Down | -0.1172618733 |
| GSE13712_STATIC | Down | -0.0685029400 |
| GSE19018 | Up | 0.0734115327 |
| GSE19899_A1 | Down | -0.3969626090 |
| GSE19899_A2 | Down | -0.3352329642 |
| PubMed_21979375_A1 | Up | 0.0177933499 |
| PubMed_21979375_A2 | Down | -0.2969958094 |
| GSE35957 | Up | 0.1284769599 |
| GSE36640 | Down | -0.1069971429 |
| GSE54402 | Down | -0.1655499196 |
| GSE9593 | Down | -0.0192117279 |
| GSE43922 | Down | -0.3986696645 |
| GSE24585 | Down | -0.1695050314 |
| GSE37065 | Down | -0.1715722956 |
| GSE28863_A1 | Down | -0.1108120025 |
| GSE28863_A2 | Up | 0.1217203882 |
| GSE28863_A3 | Down | -0.4736969324 |
| GSE28863_A4 | Down | -0.1630626714 |
| GSE48662 | Down | -0.3744492770 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-148b-3p | MIMAT0000759 | MIRT019265 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-let-7c-5p | MIMAT0000064 | MIRT051792 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
