HCSGD entry for ENDOU


1. General information

Official gene symbolENDOU
Entrez ID8909
Gene full nameendonuclease, polyU-specific
Other gene symbolsP11 PP11 PRSS26
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003723RNA bindingIDAmolecular_function
GO:0004521Endoribonuclease activityIDAmolecular_function
GO:0005044Scavenger receptor activityIEAmolecular_function
GO:0005576Extracellular regionTAScellular_component
GO:0005615Extracellular spaceTAScellular_component
GO:0005737CytoplasmIDA TAScellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0006508ProteolysisIDAbiological_process
GO:0006955Immune responseIEAbiological_process
GO:0007565Female pregnancyIEPbiological_process
GO:0008083Growth factor activityNASmolecular_function
GO:0008236Serine-type peptidase activityIDAmolecular_function
GO:0016788Hydrolase activity, acting on ester bondsIEAmolecular_function
GO:0030145Manganese ion bindingTASmolecular_function
GO:0030247Polysaccharide bindingIEAmolecular_function
GO:0090305Nucleic acid phosphodiester bond hydrolysisIDAbiological_process
GO:0090501RNA phosphodiester bond hydrolysisIDAbiological_process
GO:0090502RNA phosphodiester bond hydrolysis, endonucleolyticIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.54854745260.89326695790.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0633980341
GSE13712_SHEARUp0.1372865881
GSE13712_STATICUp0.0043844620
GSE19018Up0.3478228529
GSE19899_A1Up0.0444369423
GSE19899_A2Up0.0749915556
PubMed_21979375_A1Up0.1660928941
PubMed_21979375_A2Down-0.0436574194
GSE35957Down-0.0127779174
GSE36640Up0.0723929940
GSE54402Down-0.0163956316
GSE9593Down-0.0679624904
GSE43922Up0.0137500677
GSE24585Up0.1169464198
GSE37065Down-0.1702795837
GSE28863_A1Down-0.0552129218
GSE28863_A2Up0.1195749238
GSE28863_A3Up0.1828295902
GSE28863_A4Up0.1349400110
GSE48662Down-0.0890498749

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017902MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.