HCSGD entry for MTMR2

1. General information

Official gene symbolMTMR2
Entrez ID8898
Gene full namemyotubularin related protein 2
Other gene symbolsCMT4B CMT4B1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002091Negative regulation of receptor internalizationIEA ISSbiological_process
GO:0004725Protein tyrosine phosphatase activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005774Vacuolar membraneIEAcellular_component
GO:0005829CytosolIEA ISS TAScellular_component
GO:0006470Protein dephosphorylationNASbiological_process
GO:0006644Phospholipid metabolic processTASbiological_process
GO:0006661Phosphatidylinositol biosynthetic processTASbiological_process
GO:0008021Synaptic vesicleIEA ISScellular_component
GO:0008138Protein tyrosine/serine/threonine phosphatase activityNASmolecular_function
GO:0030424AxonIEA ISScellular_component
GO:0030425DendriteISScellular_component
GO:0031642Negative regulation of myelinationIEAbiological_process
GO:0031901Early endosome membraneIEAcellular_component
GO:0032288Myelin assemblyIEAbiological_process
GO:0042803Protein homodimerization activityIEAmolecular_function
GO:0043197Dendritic spineISScellular_component
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045806Negative regulation of endocytosisISSbiological_process
GO:0046855Inositol phosphate dephosphorylationIEAbiological_process
GO:0046856Phosphatidylinositol dephosphorylationIEAbiological_process
GO:0048666Neuron developmentIEAbiological_process
GO:0051262Protein tetramerizationIEAbiological_process
GO:0052866Phosphatidylinositol phosphate phosphatase activityIEAmolecular_function
GO:0090394Negative regulation of excitatory postsynaptic membrane potentialIEA ISSbiological_process
GO:0097060Synaptic membraneIEA ISScellular_component
GO:0097062Dendritic spine maintenanceIEA ISSbiological_process
GO:0097481Neuronal postsynaptic densityIEA ISScellular_component
GO:2000643Positive regulation of early endosome to late endosome transportIEA ISSbiological_process
GO:2000645Negative regulation of receptor catabolic processIEA ISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.99333195550.00772965690.99999024730.1758446845

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.3794264440
GSE13712_SHEARDown-0.5785177318
GSE13712_STATICDown-0.4732450125
GSE19018Down-0.3355170475
GSE19899_A1Down-0.2926775996
GSE19899_A2Down-0.5056282101
PubMed_21979375_A1Up0.2738541948
PubMed_21979375_A2Up0.2368781204
GSE35957Down-0.2990118858
GSE36640Down-0.8377143418
GSE54402Down-0.3465023064
GSE9593Down-0.5269758563
GSE43922Up0.0531735545
GSE24585Down-0.3787781520
GSE37065Down-0.0316566599
GSE28863_A1Down-0.2789460527
GSE28863_A2Down-0.1833587583
GSE28863_A3Down-0.6943536411
GSE28863_A4Up0.0452444606
GSE48662Down-0.5133175909

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-34a-5pMIMAT0000255MIRT047348CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.